Leukocytes are known to have a number of biologic effects associated with allogeneic blood transfusion ❚Table 1❚. The potential clinical importance of these effects, which are the focus of current debate over the merits of “universal” leukocyte reduction (leukoreduction; cellular components with <5 × 106 leukocytes) include the following: febrile-asso-ciated transfusion reactions (FATRs), transfusion-related alloimmunization to platelets, and transfusion-related immunomodulation. Several recent reviews1,2 of this topic, along with commentaries3-6 about the use of leukocyte-depleted blood components, have been published. The Blood Products Advisory Committee (BPAC) to the US Food and Drug Administration (FDA) voted 13-0 on September 18, 1...
Leukoreduction, filtering white blood cells from transfusion blood, effectively avoids leukocyte-rel...
Objective: To assess whether introduction of universal leukodepletion (ULD) of red blood cells (RBCs...
Summary: Patients receiving multiple whole blood transfusions often experience adverse clinical Symp...
The improvement of transfusion medicine technology is an ongoing process primarily directed at incre...
SUBJECT: In order to assess the impact of leukocyte reduction, all transfusion reactions reported at...
Removal of leucocytes from various blood products has been shown to minimize Febrile nonhemolytic tr...
Cervia et al. [1] review the evidence that removal of leukocytes from transfused blood by adherence ...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72881/1/j.1537-2995.2001.41101310.x.pd
Allogeneic blood components are commonly transfused in trauma, surgery, and intensive care units and...
Substitution of transfused platelet concentrates are often accused to cause HLA-antibody development...
BACKGROUND: The pathogenesis of posttransfusion purpura (PTP) and transfusion-associated graft-versu...
Background: Blood transfusions have always been associated with a number of adverse outcomes which h...
Randomized controlled trials have shown a reduction in platelet alloimmunization and refractoriness ...
textabstractAfter the introduction of blood component therapy in the 1960s, more and more attention ...
403-407Leukoreduction, filtering white blood cells from transfusion blood, effectively avoids leukoc...
Leukoreduction, filtering white blood cells from transfusion blood, effectively avoids leukocyte-rel...
Objective: To assess whether introduction of universal leukodepletion (ULD) of red blood cells (RBCs...
Summary: Patients receiving multiple whole blood transfusions often experience adverse clinical Symp...
The improvement of transfusion medicine technology is an ongoing process primarily directed at incre...
SUBJECT: In order to assess the impact of leukocyte reduction, all transfusion reactions reported at...
Removal of leucocytes from various blood products has been shown to minimize Febrile nonhemolytic tr...
Cervia et al. [1] review the evidence that removal of leukocytes from transfused blood by adherence ...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72881/1/j.1537-2995.2001.41101310.x.pd
Allogeneic blood components are commonly transfused in trauma, surgery, and intensive care units and...
Substitution of transfused platelet concentrates are often accused to cause HLA-antibody development...
BACKGROUND: The pathogenesis of posttransfusion purpura (PTP) and transfusion-associated graft-versu...
Background: Blood transfusions have always been associated with a number of adverse outcomes which h...
Randomized controlled trials have shown a reduction in platelet alloimmunization and refractoriness ...
textabstractAfter the introduction of blood component therapy in the 1960s, more and more attention ...
403-407Leukoreduction, filtering white blood cells from transfusion blood, effectively avoids leukoc...
Leukoreduction, filtering white blood cells from transfusion blood, effectively avoids leukocyte-rel...
Objective: To assess whether introduction of universal leukodepletion (ULD) of red blood cells (RBCs...
Summary: Patients receiving multiple whole blood transfusions often experience adverse clinical Symp...