Translating lifestyle intervention to practice in obese patients with type 2 diabetes

OBJECTIVE — To assess the efficacy of a lifestyle intervention program that can be readily translated into clinical practice for obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS — The study consisted of a 12-month random-ized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI 27 kg/m2). Participants were randomized to lifestyle case management or usual care. Case manage-ment entailed individual and group education, support, and referral by registered dietitians; intervention cost was $350 per person. Individuals treated with usual care received educational material. Both groups received ongoing primary care. Outcomes were difference between groups for change in weight (kilograms), waist circumference (centimeters), HbA1c, fasting lipid levels, use of prescription medications, and health-related quality of life. RESULTS — Case management resulted in greater weight loss (P 0.001), reduced waist circumference (P 0.001), reduced HbA1c level (P 0.02), less use of prescription medications (P 0.03), and improved health-related quality of life (P 0.001) compared with usual care. The 12-month group difference in weight loss and waist circumference was 3.0 kg (95 % CI5.4 to 0.6) and –4.2 cm (6.8 to –1.6). HbA1c differences were greatest at 4 months (0.59%