Add to ORKGBackground: Women with deleterious mutations in BRCA genes are at increased risk of breast cancer. However, the penetrance of the genetic trait may be regulated through environmental factors. This multi-national case-only study tested the interaction between oral contraceptive use and genetic susceptibility in the occurrence of breast cancer. Methods: We recruited 3,123 patients diagnosed with breast cancer before the age of 45 years. Participants were classified according to their probability of carrying a BRCA mutation on the basis of their family history of breast and ovarian cancer. According to a case-only approach, the frequency of relevant expo-sures among breast cancer cases with high probabilit
Background: Ovarian cancer risk in BRCA1 and BRCA2 mutation carriers has been shown to decrease with...
BACKGROUND: Several of the known risk factors for ovarian cancer are thought to act through their ef...
Background: Multiparity and breast-feeding reduce breast cancer risk, whereas oral contraceptive use...
Background: Oral contraceptive use has been associated with an increase in the risk of breast cancer...
Background: Women with BRCA1 or BRCA2 mutations are at increased risk of breast and ovarian cancer. ...
Purpose BRCA mutation carriers have an increased risk of developing breast or ovarian cancer. Oral c...
Background: BRCA1 and BRCA2 mutation carriers are at high risk of breast and ovarian cancer. Oral co...
Women with mutations of the genes BRCA1 or BRCA2 are at increased risk of ovarian cancer. Oral contr...
Purpose Earlier studies have shown that endogenous gonadal hormones play an important role in the et...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepara...
Background BRCA1 and BRCA2 (BRCA) mutation carriers face a high lifetime risk of developing ovarian ...
Oral contraceptive (OC) use in young women has been associated with an increased risk of breast canc...
It is not clear if early oral contraceptive use increases the risk of breast cancer among young wome...
Background: Ovarian cancer risk in BRCA1 and BRCA2 mutation carriers has been shown to decrease with...
BACKGROUND: Several of the known risk factors for ovarian cancer are thought to act through their ef...
Background: Multiparity and breast-feeding reduce breast cancer risk, whereas oral contraceptive use...
Background: Oral contraceptive use has been associated with an increase in the risk of breast cancer...
Background: Women with BRCA1 or BRCA2 mutations are at increased risk of breast and ovarian cancer. ...
Purpose BRCA mutation carriers have an increased risk of developing breast or ovarian cancer. Oral c...
Background: BRCA1 and BRCA2 mutation carriers are at high risk of breast and ovarian cancer. Oral co...
Women with mutations of the genes BRCA1 or BRCA2 are at increased risk of ovarian cancer. Oral contr...
Purpose Earlier studies have shown that endogenous gonadal hormones play an important role in the et...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepara...
Background BRCA1 and BRCA2 (BRCA) mutation carriers face a high lifetime risk of developing ovarian ...
Oral contraceptive (OC) use in young women has been associated with an increased risk of breast canc...
It is not clear if early oral contraceptive use increases the risk of breast cancer among young wome...
Background: Ovarian cancer risk in BRCA1 and BRCA2 mutation carriers has been shown to decrease with...
BACKGROUND: Several of the known risk factors for ovarian cancer are thought to act through their ef...
Background: Multiparity and breast-feeding reduce breast cancer risk, whereas oral contraceptive use...