Langerhans cells (LC) are bone-marrow derived dendritic cells that constitutively express class II major histocompatibility antigens (HLA-DR in humans, 1-3). LC remain in the epidermis for a period and migrate through lymphatics to the paracortical areas of lymph nodes, where their dendritic extensions are closely opposed to T-lymphocytes; in this site they are known as interdigitating cells (4). Dendritic cells of the LC lineage efficiently induce contact hypersensitivity (5). The number of LC in the skin is increased in humans with contact dermatitis (6). These findings have led to the suggestion that LC are the principal antigen-presenting cells (APC) in the skin (1-5). Expression of class II MHC glycoproteins is one requirement for APC;...
Dermal cells are capable of initiating contact-hypersensitivity responses but the precise identifica...
Beyond antigen processing and presentation, antigenpresenting cells must convey additional signals t...
Langerhans cells are the prototype of antigen presenting cell, their role is to work as sentinel in ...
Epidermal Langerhans cells (LC) are related to certain cells of the monocyte-macrophage lineage and ...
Langerhans cells (LCs) are professional antigen-presenting cells (APCs) residing in the epidermis. D...
Epidermal Langerhans cells are dendritic bone marrow-derived cells which synthesize and express Ia a...
Epidermal Langerhans cells (LC) are Birbeck granule-containing bone-marrow-derived cells, which are ...
Langerhans cells (LCs) are professional antigen presenting cells (APCs) residing in the epidermis. D...
Allergens or antigens when introduced on or in the skin may become localized at the surface of and i...
Langerhans-cell-enriched epidermal cell preparations, when pulsed with antigen, can induce prolifera...
Langerhans cells (LCs) are antigen-presenting dendritic cells (DCs) that reside in epithelia. The be...
Langerhans cells constitute a minor cell population within the mammalian epidermis. This paper defin...
Few data are available regarding the role of human skin dendritic cells (DCs) in driving T-cell resp...
he notion that dendritic cells (DCs) are uniquely capable of inducing naïve T cells to proliferate a...
Langerhans cells (LC) are a subpopulation of dendritic cells residing in skin and mucosal epi-theliu...
Dermal cells are capable of initiating contact-hypersensitivity responses but the precise identifica...
Beyond antigen processing and presentation, antigenpresenting cells must convey additional signals t...
Langerhans cells are the prototype of antigen presenting cell, their role is to work as sentinel in ...
Epidermal Langerhans cells (LC) are related to certain cells of the monocyte-macrophage lineage and ...
Langerhans cells (LCs) are professional antigen-presenting cells (APCs) residing in the epidermis. D...
Epidermal Langerhans cells are dendritic bone marrow-derived cells which synthesize and express Ia a...
Epidermal Langerhans cells (LC) are Birbeck granule-containing bone-marrow-derived cells, which are ...
Langerhans cells (LCs) are professional antigen presenting cells (APCs) residing in the epidermis. D...
Allergens or antigens when introduced on or in the skin may become localized at the surface of and i...
Langerhans-cell-enriched epidermal cell preparations, when pulsed with antigen, can induce prolifera...
Langerhans cells (LCs) are antigen-presenting dendritic cells (DCs) that reside in epithelia. The be...
Langerhans cells constitute a minor cell population within the mammalian epidermis. This paper defin...
Few data are available regarding the role of human skin dendritic cells (DCs) in driving T-cell resp...
he notion that dendritic cells (DCs) are uniquely capable of inducing naïve T cells to proliferate a...
Langerhans cells (LC) are a subpopulation of dendritic cells residing in skin and mucosal epi-theliu...
Dermal cells are capable of initiating contact-hypersensitivity responses but the precise identifica...
Beyond antigen processing and presentation, antigenpresenting cells must convey additional signals t...
Langerhans cells are the prototype of antigen presenting cell, their role is to work as sentinel in ...