A serology-based tiered approach has, to date, provided the most effective means of laboratory confirmation of clinically sus-pected cases of Lyme disease, but it lacks sensitivity in the early stages of disease and is often dependent on subjectively scored immunoblots. We recently demonstrated the use of immuno-PCR (iPCR) for detecting Borrelia burgdorferi antibodies in pa-tient serum samples that were positive for Lyme disease. To better understand the performance of the Lyme disease iPCR assay, the repeatability and variability of the background of the assay across samples from a healthy population (n 36) were analyzed. Both of these parameters were found to have coefficients of variation of<3%. Using eight antigen-specific iPCR assa...
Lyme disease patients would greatly benefit from a timely, sensitive, and specific molecular diagnos...
The systematically difficult task of diagnosing Lyme disease can be simplified by sensitive and spec...
The diagnoses of Lyme disease based on clinical manifestations, serological findings and detection o...
A serology-based tiered approach has, to date, provided the most effective means of laboratory confi...
Lyme disease is the fastest-growing zoonotic disease in North America. Current methods for detection...
Lyme borreliosis, more commonly referred to as Lyme disease, is the fastest growing zoonotic disease...
Lyme borreliosis, more commonly referred to as Lyme disease, is the fastest growing zoonotic disease...
The objective was to examine the prevalence of Borrelia antibodies among symptomatic individuals wit...
The cause of Lyme disease, Borrelia burgdorferi, was discovered in 1983. A 2-tiered testing protocol...
An ELISA containing a purified flagellar antigen from Borrelia burgdorferi (FLA-ELISA) was evaluated...
The cause of Lyme disease, Borrelia burgdorferi, was discovered in 1983. A 2-tiered testing protocol...
Accurate laboratory diagnosis of Lyme disease (Lyme borreliosis), caused by the spirochete Borrelia ...
Accurate laboratory diagnosis of Lyme disease (Lyme borreliosis), caused by the spirochete Borrelia ...
Serologic testing is the standard for laboratory diagnosis and confirmation of Lyme disease. Serodia...
The diagnoses of Lyme disease based on clinical manifestations, serological findings and detection o...
Lyme disease patients would greatly benefit from a timely, sensitive, and specific molecular diagnos...
The systematically difficult task of diagnosing Lyme disease can be simplified by sensitive and spec...
The diagnoses of Lyme disease based on clinical manifestations, serological findings and detection o...
A serology-based tiered approach has, to date, provided the most effective means of laboratory confi...
Lyme disease is the fastest-growing zoonotic disease in North America. Current methods for detection...
Lyme borreliosis, more commonly referred to as Lyme disease, is the fastest growing zoonotic disease...
Lyme borreliosis, more commonly referred to as Lyme disease, is the fastest growing zoonotic disease...
The objective was to examine the prevalence of Borrelia antibodies among symptomatic individuals wit...
The cause of Lyme disease, Borrelia burgdorferi, was discovered in 1983. A 2-tiered testing protocol...
An ELISA containing a purified flagellar antigen from Borrelia burgdorferi (FLA-ELISA) was evaluated...
The cause of Lyme disease, Borrelia burgdorferi, was discovered in 1983. A 2-tiered testing protocol...
Accurate laboratory diagnosis of Lyme disease (Lyme borreliosis), caused by the spirochete Borrelia ...
Accurate laboratory diagnosis of Lyme disease (Lyme borreliosis), caused by the spirochete Borrelia ...
Serologic testing is the standard for laboratory diagnosis and confirmation of Lyme disease. Serodia...
The diagnoses of Lyme disease based on clinical manifestations, serological findings and detection o...
Lyme disease patients would greatly benefit from a timely, sensitive, and specific molecular diagnos...
The systematically difficult task of diagnosing Lyme disease can be simplified by sensitive and spec...
The diagnoses of Lyme disease based on clinical manifestations, serological findings and detection o...