PHD2 serves as oxygen sensor that rescues blood supply by regulating vessel formation and shape in case of oxygen shortage. However, it is unknown whether PHD2 can influence arteriogenesis. By using hindlimb ischemia as a model, we studied the role of PHD2 in collateral artery growth, a process that compensates the lack of blood flow i
Arteriosclerotic vascular disease is the most common cause of death and a major cause of disability ...
Background-—Hypertension induces cardiovascular hypertrophy and fibrosis. Infiltrated macrophages ar...
SummaryA key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormali...
PHD2 serves as an oxygen sensor that rescues blood supply by regulating vessel formation and shape i...
The authors are thankful to Dr. P. Carmeliet for scientific discussion and support. VE-Cadherin:Cre...
Occlusion of the main arterial route redirects blood flow to the collateral circulation. We previous...
Occlusion of the main arterial route redirects blood flow to the collateral circulation. We previous...
Abstract Background Angiopoietin-2 (Ang-2), a ligand of the Tie-2 receptor, plays an important role ...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
Ischemia causes an inflammatory response that is intended to restore perfusion and homeostasis yet o...
AIMS: Atherosclerotic plaque hypoxia is detrimental for macrophage function. Prolyl hydroxylases (PH...
The prolyl-4-hydroxylase domain (PHD) enzymes are regarded as the molecular oxygen sensors. There is...
Arteriosclerotic vascular disease is the most common cause of death and a major cause of disability ...
Background-—Hypertension induces cardiovascular hypertrophy and fibrosis. Infiltrated macrophages ar...
SummaryA key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormali...
PHD2 serves as an oxygen sensor that rescues blood supply by regulating vessel formation and shape i...
The authors are thankful to Dr. P. Carmeliet for scientific discussion and support. VE-Cadherin:Cre...
Occlusion of the main arterial route redirects blood flow to the collateral circulation. We previous...
Occlusion of the main arterial route redirects blood flow to the collateral circulation. We previous...
Abstract Background Angiopoietin-2 (Ang-2), a ligand of the Tie-2 receptor, plays an important role ...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
A key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormalities in...
Ischemia causes an inflammatory response that is intended to restore perfusion and homeostasis yet o...
AIMS: Atherosclerotic plaque hypoxia is detrimental for macrophage function. Prolyl hydroxylases (PH...
The prolyl-4-hydroxylase domain (PHD) enzymes are regarded as the molecular oxygen sensors. There is...
Arteriosclerotic vascular disease is the most common cause of death and a major cause of disability ...
Background-—Hypertension induces cardiovascular hypertrophy and fibrosis. Infiltrated macrophages ar...
SummaryA key function of blood vessels, to supply oxygen, is impaired in tumors because of abnormali...