Letter to the Editor (case report) doi:10.1093/rheumatology/kev197

Successful treatment with canakinumab of a paediatric patient with resistant Behçet’s disease SIR, Behçet’s disease (BD) is a systemic vasculitis char-acterized by a wide clinical spectrum including recurrent oral and genital ulceration, uveitis, vascular, neurological, articular, renal and gastrointestinal manifestations [1]. Treatment of BD depends on the clinical manifestation and organ involvement. Although colchicine, NSAIDs and topical steroids are often sufficient for mucocuta-neous and joint involvement, a more aggressive approach with immunosuppressive drugs is necessary for severe manifestations such as posterior uveitis, retinal vasculitis, recurrent fevers, vascular, neurological and gastrointes-tinal involvement. However, some patients still have refractory disease, flares or irreversible organ damage