Clear sex differences exist in asthma and atopy with a preponderance of boys before puberty. There is a reversal of this sex ratio during puberty with girls having more asthma and atopy throughout the reproductive years. Elucidating the reasons for the switch in the sex ratio should provide fresh insights into asthma and atopy with a real prospect of novel therapies for these troublesome diseases. The challenge is to match the epidemiology and physiology with the accumulating scientific knowledge on gender differences in immune responses. Hormonal changes have been implicated in the reversal of the sex ratio. Testosterone is an immunosuppressant and is likely to be protective, while female sex steroids are proinflammatory and will increase ...
Background: Although pre-puberty asthma is more prevalent in males, after puberty through middle-age...
BackgroundAlthough pre-puberty asthma is more prevalent in males, after puberty through middle-age, ...
Asthma is a common chronic disease that affects over 300 million people worldwide, resulting in a co...
A gender-related disparity exists in asthma morbidity and mortality, which shifts at around puberty ...
A multitude of evidence has suggested the differential incidence, prevalence and severity of asthma ...
Sex-based differences in bronchial asthma can already be observed in childhood, at which time allerg...
International audienceAn individual's sex (nominally 'male' or 'female', based on biological attribu...
A gender-related disparity exists in asthma morbidity and mortality, which shifts at around puberty ...
Background: Asthma is a chronic inflammatory airway disease that has a higher prevalence in boys tha...
In the transition from childhood to adulthood there is a reversal in the sex distribution of asthma ...
A bulk of literature demonstrated that respiratory allergy, and especially asthma, is prevalent in m...
Gender differences in the development and prevalence of human diseases have long been recognized. Im...
A number of studies have shown gender differences in the prevalence of wheeze and asthma. The aim of...
Many epidemiological studies suggest that women are at increased risk of developing adult-onset asth...
Abstract There is good evidence for gender-specific differences in asthma regarding all affected are...
Background: Although pre-puberty asthma is more prevalent in males, after puberty through middle-age...
BackgroundAlthough pre-puberty asthma is more prevalent in males, after puberty through middle-age, ...
Asthma is a common chronic disease that affects over 300 million people worldwide, resulting in a co...
A gender-related disparity exists in asthma morbidity and mortality, which shifts at around puberty ...
A multitude of evidence has suggested the differential incidence, prevalence and severity of asthma ...
Sex-based differences in bronchial asthma can already be observed in childhood, at which time allerg...
International audienceAn individual's sex (nominally 'male' or 'female', based on biological attribu...
A gender-related disparity exists in asthma morbidity and mortality, which shifts at around puberty ...
Background: Asthma is a chronic inflammatory airway disease that has a higher prevalence in boys tha...
In the transition from childhood to adulthood there is a reversal in the sex distribution of asthma ...
A bulk of literature demonstrated that respiratory allergy, and especially asthma, is prevalent in m...
Gender differences in the development and prevalence of human diseases have long been recognized. Im...
A number of studies have shown gender differences in the prevalence of wheeze and asthma. The aim of...
Many epidemiological studies suggest that women are at increased risk of developing adult-onset asth...
Abstract There is good evidence for gender-specific differences in asthma regarding all affected are...
Background: Although pre-puberty asthma is more prevalent in males, after puberty through middle-age...
BackgroundAlthough pre-puberty asthma is more prevalent in males, after puberty through middle-age, ...
Asthma is a common chronic disease that affects over 300 million people worldwide, resulting in a co...