Inspiratory Muscle Strength Training Improves Weaning Outcome in Failure to Wean Patients

study investigated the effect of inspiratory muscle strength training (IMST) on inspiratory motor drive [mouth occlusion pressure at 0.1 s (P0.1)] and respiratory-related evoked po-tentials (RREP). It was hypothesized that, if IMST increased inspiratory muscle strength, inspiratory motor drive would decrease. If motor drive were related to the RREP, it was further hypothesized that an IMST-related decrease in drive would change RREP latency and/or amplitude. Twenty-three subjects received IMST at 75 % of their maximal inspiratory pressure (PImax) with the use of a pressure threshold valve. IMST consisted of four sets of six breaths daily for 4 wk. P0.1 and the RREP were recorded before and after IMST. Post-training, PImax increased significantly by 36.0 2.7%. P0.1 decreased significantly by 21.9 5.2%. The increase in PImax was significantly correlated to the decrease in P0.1. RRE