Analytical Review Leukemia or Lymphoma Occurring Subsequent to an Autoimmune Disease

S EVERAL AUTHORS HAVE PROPOSED that patients with autoimmunedisorders may develop either leukemia or one of the lymphoreticular malignancies at an excessive rate.4 This paper examines this proposal by means of a review of the case reports in the literature and an analysis of the mortality experience of published series of patients with various auto-immune disorders through December 1965. METHODS Case reports of leukemia or lymphoma occurring subsequent to ar autoimmune disease were obtained by a review of the English literature. Diseases were included in th