Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fibrotic process of Crohn’s disease (CD). Mesenchymal smooth muscle cells (SMCs) de-differentiation, driven by Platelet-derived growth factor (PDGF) that counteracts Transforming growth factor (TGF-β) has been studied in vascular muscle. The role of SMCs in intestinal fibrogenesis is still not clearly eluci-dated. Aim of the study was to evaluate the pos-sible myogenic contribution to CD fibrotic process through the comparative analysis of histological, morphometric and molecular alter-ations occurring in human smooth muscle. Ful
As a general rule, smooth muscle cells (SMC) are able to switch from a contractile phenotype to a le...
Intestinal fibrosis in inflammatory bowel disease is a dynamic, multifactorial process, which involv...
AIM: To investigate tumor necrosis factor-α (TNF-α), syndecan 1 and basic fibroblast growth factor (...
Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fibro...
<p>Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fi...
Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fibro...
Background. Several enteropathies are characterized by an intestinal fibrosis that may lead to steno...
BACKGROUND Intestinal fibrosis and subsequent stricture formation represent frequent complications ...
Inflammatory bowel diseases (IBD) are characterized by an intestinal fibrosis that may lead to steno...
Fibrogenesis in inflammatory bowel diseases is a complex phenomenon aimed at mucosal repair. However...
The notion that smooth muscle function is altered in inflammation is prompted by clinical observatio...
Background: Despite significant progress in the research of fibrosis in various organs, fibrosis rem...
Background. Intestinal fibrosis is a common complication of inflammatory bowel diseases, affecting p...
Background: Intestinal fibrosis in Crohn’s disease (CD) is considered to be irreversible and induces...
Background and Aims: Crohn's disease is a chronic inflammatory disorder of the intestine and often l...
As a general rule, smooth muscle cells (SMC) are able to switch from a contractile phenotype to a le...
Intestinal fibrosis in inflammatory bowel disease is a dynamic, multifactorial process, which involv...
AIM: To investigate tumor necrosis factor-α (TNF-α), syndecan 1 and basic fibroblast growth factor (...
Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fibro...
<p>Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fi...
Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fibro...
Background. Several enteropathies are characterized by an intestinal fibrosis that may lead to steno...
BACKGROUND Intestinal fibrosis and subsequent stricture formation represent frequent complications ...
Inflammatory bowel diseases (IBD) are characterized by an intestinal fibrosis that may lead to steno...
Fibrogenesis in inflammatory bowel diseases is a complex phenomenon aimed at mucosal repair. However...
The notion that smooth muscle function is altered in inflammation is prompted by clinical observatio...
Background: Despite significant progress in the research of fibrosis in various organs, fibrosis rem...
Background. Intestinal fibrosis is a common complication of inflammatory bowel diseases, affecting p...
Background: Intestinal fibrosis in Crohn’s disease (CD) is considered to be irreversible and induces...
Background and Aims: Crohn's disease is a chronic inflammatory disorder of the intestine and often l...
As a general rule, smooth muscle cells (SMC) are able to switch from a contractile phenotype to a le...
Intestinal fibrosis in inflammatory bowel disease is a dynamic, multifactorial process, which involv...
AIM: To investigate tumor necrosis factor-α (TNF-α), syndecan 1 and basic fibroblast growth factor (...