The interactions of levofloxacin, a pyridonecarboxylic acid an-tibacterial drug, with the organic cation transport systems ex-pressed in a pig kidney epithelial cell line, LLC-PK1, were examined. The transcellular transport of tetraethylammonium was remarkably inhibited by levofloxacin, accompanied by a marked increase in the cellular accumulation of tetraethylam-monium in the LLC-PK1 monolayers grown on collagen-coated membrane filters. The results obtained by efflux and uptake of tetraethylammonium revealed that levofloxacin drastically in-hibited the apical transport activity rather than the basolateral uptake of tetraethylammonium. Under conditions in which the apical efflux of tetraethylammonium was blocked by pretreat-ment with p-chlo...
It was reported previously that specific levofloxacin uptake in Caco- 2 cells was inhibited by nicot...
The transport of a group of quinolone antibiotics across the human intestinal model, Caco-2 cells, w...
The transport characteristics of six fluoroquinolones (FQs) with various lipophilicities were compar...
The transport of quinolone antibacterial drugs by LLC-PK1 monolayers was examined to characterize th...
Ofloxacin, a pyndonecarboxylic acid derivative, was examined for its effects on the transport of tet...
We investigated whether the LLC-PK1 epithelial cell line (which shows many characteristics of proxim...
Grepafloxacin and levofloxacin transport by Caco-2 cell mono-layers was examined to characterize the...
Fluoroquinolones (FQs) are important antimicrobials that exhibit activity against a wide range of ba...
Fluoroquinolones (FQs) are important antimicrobials that exhibit activity against a wide range of ba...
Contraluminal organic anion and cation transport in the proximal renal tubule: V. Interaction with s...
D ow nloaded from 2 Abstract 19 Fluoroquinolones (FQs) are important antimicrobials that exhibit act...
The cephalosponn antibiotics cephaloridine and cefazolin were examined for their effects on the tran...
Cellular and molecular aspects of drug transport in the kidney. The kidney plays an important role i...
Using the stopped flow tubular lumen or peritubular capillary microperfusion method, the apparent Ki...
This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal ...
It was reported previously that specific levofloxacin uptake in Caco- 2 cells was inhibited by nicot...
The transport of a group of quinolone antibiotics across the human intestinal model, Caco-2 cells, w...
The transport characteristics of six fluoroquinolones (FQs) with various lipophilicities were compar...
The transport of quinolone antibacterial drugs by LLC-PK1 monolayers was examined to characterize th...
Ofloxacin, a pyndonecarboxylic acid derivative, was examined for its effects on the transport of tet...
We investigated whether the LLC-PK1 epithelial cell line (which shows many characteristics of proxim...
Grepafloxacin and levofloxacin transport by Caco-2 cell mono-layers was examined to characterize the...
Fluoroquinolones (FQs) are important antimicrobials that exhibit activity against a wide range of ba...
Fluoroquinolones (FQs) are important antimicrobials that exhibit activity against a wide range of ba...
Contraluminal organic anion and cation transport in the proximal renal tubule: V. Interaction with s...
D ow nloaded from 2 Abstract 19 Fluoroquinolones (FQs) are important antimicrobials that exhibit act...
The cephalosponn antibiotics cephaloridine and cefazolin were examined for their effects on the tran...
Cellular and molecular aspects of drug transport in the kidney. The kidney plays an important role i...
Using the stopped flow tubular lumen or peritubular capillary microperfusion method, the apparent Ki...
This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal ...
It was reported previously that specific levofloxacin uptake in Caco- 2 cells was inhibited by nicot...
The transport of a group of quinolone antibiotics across the human intestinal model, Caco-2 cells, w...
The transport characteristics of six fluoroquinolones (FQs) with various lipophilicities were compar...