Bangladesh Journal of Pharmacology

Mandookaparni (Centella asiatica) is a medicinal plant used in Ayurveda since thousands of year and listed in the historic Shusruta Samhita, an ancient Ayurvedic medicinal text. The fortified form of C. asiatica is prepared by giving Bhavana (triturating with decoction prepared from C. asiatica leaves) to the C. asiatica powder. The herb C. asiatica is extensively used in various parts of India for various ailments like headache, body ache, asthma (Chopra et. al., 1986). It is also reported that C. asiatica used in various mental disorders and is regarded as one of the best psycho-tropic drugs. C. asiatica and its chemical constituent asiaticoside were evaluated for its anxiolytic activity in rats (Wijeweera et al., 2006). The anxiety disorders are increasing in general population and there is a grea