Add to ORKGOBJECTIVE In China, vinorelbine plus an anthracycline is a common neoadjuvant regimen for local ly-advanced breast cancer (LABC). Pegylated liposomal doxorubicin (PLD) is an alternate anthracycline formulation with a more favorable safety profi le compared with conventional anthracyclines. METHODS In this open-label trial, 61 women with LABC received up to 6 cycles of PLD 30 mg/m2 on Day 1 and vinorelbine 25 mg/m2 on Days 1 and 8 every 21 days. Hormone receptor and/or HER2 status was not routinely available. RESULTS The overall clinical response rate (primary effi cacy endpoint) was 80 % (95 % CI: 68%-89%). Two patients achieved a pathological complete respons
Simple Summary Anthracyclines are among the most active chemotherapies in breast cancer (BC). Howeve...
Simple Summary Anthracyclines are among the most active chemotherapies in breast cancer (BC). Howeve...
Background: Pegylated liposomal doxorubicin (PLD) was shown as active but less toxic compared to dox...
OBJECTIVE In China, vinorelbine plus an anthracycline is a common neoadjuvant regimen for locall...
The objective of the present study is to investigate the clinical efficacy and tolerance of vinorelb...
Breast cancer is a global issue regarding women’s health, and high incident rates remain in the Taiw...
Background: Conventional anthracyclines play an essential role for the treatment of breast cancer an...
Purpose: To explore the activity of pegylated liposomal doxorubicin (PLD) as neoadjuvant therapy of ...
Anthracycline is very effective in treatment of breast cancer, however it can cause cardiac toxicit...
In order to downstage locally advanced breast cancer, neoadjuvant chemotherapy consisting of intrave...
Background: Conventional anthracyclines, like epirubicin, are cornerstone drugs for breast cancer tr...
Abstract Background This study is a retrospective evaluation of the efficacy of neoadjuvant chemothe...
Minjun Dong,1 Liang Luo,2 Xiaogang Ying,3 Xianqiu Lu,3 Jianguo Shen,1 Zhinong Jiang,4 Linbo Wang1 1...
BACKGROUND: The aim of this study was to determine the activity of anthracycline rechallenge using p...
Anthracycline-containing regimens have demonstrated significant disease-free and overall survival be...
Simple Summary Anthracyclines are among the most active chemotherapies in breast cancer (BC). Howeve...
Simple Summary Anthracyclines are among the most active chemotherapies in breast cancer (BC). Howeve...
Background: Pegylated liposomal doxorubicin (PLD) was shown as active but less toxic compared to dox...
OBJECTIVE In China, vinorelbine plus an anthracycline is a common neoadjuvant regimen for locall...
The objective of the present study is to investigate the clinical efficacy and tolerance of vinorelb...
Breast cancer is a global issue regarding women’s health, and high incident rates remain in the Taiw...
Background: Conventional anthracyclines play an essential role for the treatment of breast cancer an...
Purpose: To explore the activity of pegylated liposomal doxorubicin (PLD) as neoadjuvant therapy of ...
Anthracycline is very effective in treatment of breast cancer, however it can cause cardiac toxicit...
In order to downstage locally advanced breast cancer, neoadjuvant chemotherapy consisting of intrave...
Background: Conventional anthracyclines, like epirubicin, are cornerstone drugs for breast cancer tr...
Abstract Background This study is a retrospective evaluation of the efficacy of neoadjuvant chemothe...
Minjun Dong,1 Liang Luo,2 Xiaogang Ying,3 Xianqiu Lu,3 Jianguo Shen,1 Zhinong Jiang,4 Linbo Wang1 1...
BACKGROUND: The aim of this study was to determine the activity of anthracycline rechallenge using p...
Anthracycline-containing regimens have demonstrated significant disease-free and overall survival be...
Simple Summary Anthracyclines are among the most active chemotherapies in breast cancer (BC). Howeve...
Simple Summary Anthracyclines are among the most active chemotherapies in breast cancer (BC). Howeve...
Background: Pegylated liposomal doxorubicin (PLD) was shown as active but less toxic compared to dox...