Chemometric Study of Retention on Binary Stationary Phases in Gas Chromatography

Using gas chromatography, data analysis is performed on a dataset consisting of 486 retention indices, 27 standards (ramified alkanes, aliphatic alcohols, and aromatic compounds), 6 pure and binary sta-tionary phases, and three temperatures. The behavior of the pure stationary phases (OV-3, OV-225, OV-61-OH, and OV-1701-OH) and the binary stationary phases (OV-3/OV-225 and OV-61-OH/OV-1701-OH) at different temperatures (608C–1008C) is investigated with factor and topological analysis. The influence of temperature and the nature of the mixed stationary phases on the retention indices is studied by correspondence factor analysis (CFA). The non-addi-tivity of the retention properties of the pure phases used as mixed phases is clearly established by CFA. The topological analysis of the substituent’s effect is investigated with a DARC/PELCO proced-ure and shows the particular influence of the stationary phase com-position on the retention. The substituent effect is measured for the pure and binary stationary phases at various temperatures. The evo-lution of the substituent effect from the pure stationary phases to the binary phases is discussed