Add to ORKGAbstract — The present study was designed to evaluate the kinetics of acetaldehyde (ACT) and its action on the cardiovascular system in rats. ACT (3, 6, 12 mg/kg i.p.) causes accumulation of this metabolite in the blood, at a concentration corresponding to that obtained from ethanol metabolism after its administration in doses of 1, 2, 4 g/kg p.o., respectively. After intraperitoneal injection of ACT there were no significant changes in blood pressure and heart rate in comparison to the control group. It appears that, in rats, ACT has no influence on the function of the cardiovascular system after the ingestion of ethanol
To determine the pharmacological importance of acetaldehyde in the actions of ethanol, this study wa...
Whereas human studies keep reporting evidence that acetaldehyde accumulation prevents alcohol drinki...
We have observed that blood acetaldehyde (AcH) levels after an ethanol dose were significantly highe...
1. 1. The activities of leucine aminotransferase (BCAT) and 2-oxoisocaproate dehydrogenase (OADH) we...
Abstract — In order to explore the influence of acetaldehyde (AcH) metabolism on the voluntary ethan...
It has been suggested that acetaldehyde has a biphasic effect on voluntary alcohol consumption. At l...
Abstract — The hepatic metabolism of acetaldehyde in carbon tetrachloride (CCI4)-intoxicated rats wa...
1. 1. The effects of ethanol and acetaldehyde upon adenine nucleotide concentrations in rat heart an...
Alcoholism is one of the major causes of non-ischemic heart damage. The myopathic state of the heart...
Whereas human studies keep reporting evidence that acetaldehyde accumulation prevents alcohol drinki...
1. 1. Protein synthesis was measured in the hearts of rats exposed to acetaldehyde vapour for 21 day...
SUMMARY To determine whether the acute cardiac depressant effects of ethanol could be attributed to ...
Acetaldehyde has long been suggested to be involved in a number of ethanol's pharmacological and beh...
Rats intoxicated with ethanol and acetaldehyde during 2 months showed increase of the thromboplasti...
It has been postulated that a number of the central effects of ethanol are mediated via ethanol meta...
To determine the pharmacological importance of acetaldehyde in the actions of ethanol, this study wa...
Whereas human studies keep reporting evidence that acetaldehyde accumulation prevents alcohol drinki...
We have observed that blood acetaldehyde (AcH) levels after an ethanol dose were significantly highe...
1. 1. The activities of leucine aminotransferase (BCAT) and 2-oxoisocaproate dehydrogenase (OADH) we...
Abstract — In order to explore the influence of acetaldehyde (AcH) metabolism on the voluntary ethan...
It has been suggested that acetaldehyde has a biphasic effect on voluntary alcohol consumption. At l...
Abstract — The hepatic metabolism of acetaldehyde in carbon tetrachloride (CCI4)-intoxicated rats wa...
1. 1. The effects of ethanol and acetaldehyde upon adenine nucleotide concentrations in rat heart an...
Alcoholism is one of the major causes of non-ischemic heart damage. The myopathic state of the heart...
Whereas human studies keep reporting evidence that acetaldehyde accumulation prevents alcohol drinki...
1. 1. Protein synthesis was measured in the hearts of rats exposed to acetaldehyde vapour for 21 day...
SUMMARY To determine whether the acute cardiac depressant effects of ethanol could be attributed to ...
Acetaldehyde has long been suggested to be involved in a number of ethanol's pharmacological and beh...
Rats intoxicated with ethanol and acetaldehyde during 2 months showed increase of the thromboplasti...
It has been postulated that a number of the central effects of ethanol are mediated via ethanol meta...
To determine the pharmacological importance of acetaldehyde in the actions of ethanol, this study wa...
Whereas human studies keep reporting evidence that acetaldehyde accumulation prevents alcohol drinki...
We have observed that blood acetaldehyde (AcH) levels after an ethanol dose were significantly highe...