Add to ORKGMotivation: RNAs fold into complex structures that are integral to the diverse mechanisms underlying RNA regulation of gene expres-sion. Recent development of transcriptome-wide RNA structure profiling through the application of structure-probing enzymes or chemicals combined with high-throughput sequencing has opened a new field that greatly expands the amount of in vitro and in vivo RNA structural information available. The resultant datasets provide the opportunity to investigate RNA structural information on a global scale. However, the analysis of high-throughput RNA structure pro-filing data requires considerable computational effort and expertise. Results: We present a new platform, StructureFold, that provides an integrated computat...
RNA structures play critical roles in regulating gene expression across all domains of life and viru...
Ribonucleic Acid (RNA) is an important cellular macromolecule vital to most if not all life on Earth...
From epigenetic regulation to protein regulation, RNAs structure is integral to a wide variety of ce...
Motivation: RNAs fold into complex structures that are integral to the diverse mechanisms under-lyin...
RNA is a key biopolymer that mechanistically drives many cellular processes. As a single-stranded mo...
We present an integrative approach, SeqFold, that combines high-throughput RNA structure profiling d...
Most RNA molecules form internal base pairs, leading to a folded secondary structure. Some of these ...
RNA is emerging as a key regulator of a plethora of biological processes. While its study has remain...
RNA structure is important for RNA function and regulation, and there is growing interest in determi...
BackgroundStructure profiling experiments provide single-nucleotide information on RNA structure. Re...
With increasing recognition of the roles RNA molecules and RNA/protein complexes play in an unexpect...
Background: RNA molecules fold into complex three-dimensional shapes, guided by the pattern of hydro...
The central hypothesis of molecular biology depicts RNA as an intermediary conveyor of genetic infor...
RNA is a key regulator of almost every cellular process, and the structures adopted by RNA molecules...
The world of regulatory RNAs is fast expanding into mainstream molecular biology as both a subject o...
RNA structures play critical roles in regulating gene expression across all domains of life and viru...
Ribonucleic Acid (RNA) is an important cellular macromolecule vital to most if not all life on Earth...
From epigenetic regulation to protein regulation, RNAs structure is integral to a wide variety of ce...
Motivation: RNAs fold into complex structures that are integral to the diverse mechanisms under-lyin...
RNA is a key biopolymer that mechanistically drives many cellular processes. As a single-stranded mo...
We present an integrative approach, SeqFold, that combines high-throughput RNA structure profiling d...
Most RNA molecules form internal base pairs, leading to a folded secondary structure. Some of these ...
RNA is emerging as a key regulator of a plethora of biological processes. While its study has remain...
RNA structure is important for RNA function and regulation, and there is growing interest in determi...
BackgroundStructure profiling experiments provide single-nucleotide information on RNA structure. Re...
With increasing recognition of the roles RNA molecules and RNA/protein complexes play in an unexpect...
Background: RNA molecules fold into complex three-dimensional shapes, guided by the pattern of hydro...
The central hypothesis of molecular biology depicts RNA as an intermediary conveyor of genetic infor...
RNA is a key regulator of almost every cellular process, and the structures adopted by RNA molecules...
The world of regulatory RNAs is fast expanding into mainstream molecular biology as both a subject o...
RNA structures play critical roles in regulating gene expression across all domains of life and viru...
Ribonucleic Acid (RNA) is an important cellular macromolecule vital to most if not all life on Earth...
From epigenetic regulation to protein regulation, RNAs structure is integral to a wide variety of ce...