Effects of endurance exercise training on muscle glycogen accumulation in humans. J.Appl.Physiol

Holloszy. Effects of endurance exercise training on muscle glycogen accumulation in humans. J. Appl. Physiol. 87(1): 222–226, 1999.—The purpose of this investigation was to determine whether endurance exercise training increases the ability of human skeletal muscle to accumulate glycogen after exercise. Subjects (4 women and 2 men, 31 6 8 yr old) performed high-intensity stationary cycling 3 days/wk and continuous running 3 days/wk for 10 wk. Muscle glycogen concentration was measured after a glycogen-depleting exer-cise bout before and after endurance training. Muscle glyco-gen accumulation rate from 15 min to 6 h after exercise was twofold higher (P, 0.05) in the trained than in the untrained state: 10.5 6 0.2 and 4.5 6 1.3 mmol·kg wet wt21 ·h21, respectively. Muscle glycogen concentration was higher (P, 0.05) in the trained than in the untrained state at 15 min, 6 h