Research Article 4-Hydroxy-17-methylincisterol from Agaricus blazei Decreased Cytokine Production and Cell Proliferation in

Copyright © 2013 Wei-Jern Tsai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Agaricus blazeiMurill is an edible and medicinal mushroom. In the previous study, we have proved that extracts of A. blazei inhibit human peripheral bloodmononuclear cell (PBMC) proliferation activated with phytohemagglutinin (PHA). Currently, we purified 4-hydroxy-17-methylincisterol (4-HM;