Patients Without Renal Failure and Nondiabetic Control Subjects and Their Association With Coronary

This study examined the role of cholesteryl ester trans-fer (CET), cholesteryl ester transfer protein (CETP) activity, and phospholipid transfer protein (PLTP) ac-tivity in the increased prevalence of coronary artery calcification (CAC) in diabetic subjects compared with nondiabetic subjects and in the loss of the sex differ-ence in CAC in diabetes. CETP activity, PLTP activity, and CET were measured in 195 type 1 diabetic subjects without renal failure and 194 nondiabetic control sub-jects of similar age (30–55 years) and sex distribution (50 % female). CAC was quantified with electron beam computed tomography. CETP activity was higher in diabetic subjects (mean 84 arbitrary units [AU]) than in nondiabetic subjects (80 AU, P 5 0.028). PLTP activity was also higher in diabetic subjects (96 AU) than i