Efficacy of a Combined Diloxanide Furoate-Metronidazole Preparation in the Treatment of

A combined formulation of diloxanide furoate and metron-idazole was used to treat amoebiasis and giardiasis (cysts and vegetative forms) in 54 patients. Of these, 34 patients had amoebiasis, 19 had giardiasis and one had mixed infec-tion. Each patient took one tablet (containing 500 mg dilox-anide furoate and 400 mg metronidazole), three times daily for 5 days, and the response to therapy was checked by clin-ical examination and by examination of fresh stools on days 3, 5 and 10. Abdominal pain was completely relieved in 91 % and 84 % of patients with amoebiasis and giardiasis, respec-tively, while parasitic clearance was 100 % in both groups. Tolerance to the drug was adequate