CLINICAL SCIENCE p, Microglobulin in Lichen Planus

The aim of the present study was to examine idiopathic lichen planus for possible changes in the serum concentration of the immunological marker 32 microglobulin (f2m), a component of HLA antigens. It was shown that serum levels of 02m were not different in lichen planus from those in controls. Although these findings do not support major systemic immunopathological changes in lichen planus, they do not exclude the involvement of local immune mechanisms. by a solid phase radio-immunoassay, * as previously described by Vincent and Revillard.23 Statistical analyses. Results were analyzed by an analysis of variance (Kruskal-Wallis test) and Student's t test and are expressed as mean serum 0l2m concentration in mg/l, plus or minus standard deviation (S.D.)