Mutual information without the influence of phylogeny or entropy dramatically improves residue contact predictio
Author summary Many biologically important protein-protein interactions are conserved over evolution...
BACKGROUND: Existing sequence alignment algorithms use heuristic scoring schemes based on biological...
Abstract—In this paper, we explore the application of information theory in DNA sequence analysis. T...
Motivation: Compensating alterations during the evolution of protein families give rise to coevolvin...
Motivation: Compensating alterations during the evolution of protein families give rise to coevolvin...
We have previously developed a method for predicting interresidue contacts using information about c...
Inferring protein-protein interactions from sequences is an important task in computational biology....
We investigate methods of estimating residue correlation within protein sequences. We begin by using...
Coevolution-based contact prediction, either directly by coevolutionary couplings resulting from glo...
Nd (2, 3) would be predicted as possessing a strong coupling signal. Columns 4 – 6 illustrate the co...
Compensatory mutations between protein residues in physical contact can manifest themselves as stati...
Direct-coupling analysis is a statistical learning method for protein contact prediction based on se...
Compensatory mutations between protein residues in physical contact can manifest themselves as stati...
ABSTRACT In this work we present a novel correlated mutations analysis (CMA) method that is signific...
<p>Contact definition 1 = A maximal distance of 8 Å between their C-beta atoms (C-alpha for glycine...
Author summary Many biologically important protein-protein interactions are conserved over evolution...
BACKGROUND: Existing sequence alignment algorithms use heuristic scoring schemes based on biological...
Abstract—In this paper, we explore the application of information theory in DNA sequence analysis. T...
Motivation: Compensating alterations during the evolution of protein families give rise to coevolvin...
Motivation: Compensating alterations during the evolution of protein families give rise to coevolvin...
We have previously developed a method for predicting interresidue contacts using information about c...
Inferring protein-protein interactions from sequences is an important task in computational biology....
We investigate methods of estimating residue correlation within protein sequences. We begin by using...
Coevolution-based contact prediction, either directly by coevolutionary couplings resulting from glo...
Nd (2, 3) would be predicted as possessing a strong coupling signal. Columns 4 – 6 illustrate the co...
Compensatory mutations between protein residues in physical contact can manifest themselves as stati...
Direct-coupling analysis is a statistical learning method for protein contact prediction based on se...
Compensatory mutations between protein residues in physical contact can manifest themselves as stati...
ABSTRACT In this work we present a novel correlated mutations analysis (CMA) method that is signific...
<p>Contact definition 1 = A maximal distance of 8 Å between their C-beta atoms (C-alpha for glycine...
Author summary Many biologically important protein-protein interactions are conserved over evolution...
BACKGROUND: Existing sequence alignment algorithms use heuristic scoring schemes based on biological...
Abstract—In this paper, we explore the application of information theory in DNA sequence analysis. T...