Bone marrow is usually dose-limiting for radioimmunotherapy. In this study, we directly estimated red marrow activity concen-tration and the self-dose component of absorbed radiation dose to red marrow based on PET/CT of 2 different 124I-labeled antibodies (cG250 and huA33) and compared the results with plasma activity concentration and plasma-based dose estimates. Methods: Two groups of patients injected with 124I-labeled monoclonal antibodies (11 patients with renal cancer receiving 124I-cG250 and 5 patients with colorectal cancer receiving 124I- huA33) were imaged by PET or PET/CT on 2 or 3 occasions after infusion. Regions of interest were drawn over several lumbar vertebrae, and red marrow activity concentration was quantified. Plasma ...
AIM: The aim of this work was the evaluation of the usefulness of 124I PET/CT sequential scans t...
Purpose: Adequate dosimetry is mandatory for effective and safe peptide receptor radionuclide therap...
Aim: In the radiation therapy, normal bone marrow is often included in radiation field inevitably. T...
Bone marrow is usually dose-limiting for radioimmunotherapy. In this study, we directly estimated re...
Red marrow is usually the dose-limiting organ during radioimmunotherapy. Several non-invasive approa...
Hematologic toxicity limits the radioactivity that may be administered for radiolabeled antibody the...
BACKGROUND: The method for red marrow dosimetry in radioimmunotherapy, in the absence of specific ac...
Noninvasive imaging techniques have been used in the past for visualization the functional activity ...
This study aimed to compare different image-based methods for bone marrow dosimetry and study the do...
Radiotherapy (RT) and chemotherapy are important treatment modalities for a variety of malignant tum...
Background Radiotherapy (RT) and chemotherapy are important treatment modalities for a variety of ma...
Calculated red marrow absorbed dose in patients receiving radioimmunotherapy (RAIT) has not been hig...
In the present study, we have measured bone marrow radioactivity using direct counting of tissues fr...
The aim of this work was the evaluation of the usefulness of 124I PET/CT sequential scans to predict...
Background: Red bone marrow (RBM) toxicity is dose-limiting in (pretargeted) radioimmunotherapy (RIT...
AIM: The aim of this work was the evaluation of the usefulness of 124I PET/CT sequential scans t...
Purpose: Adequate dosimetry is mandatory for effective and safe peptide receptor radionuclide therap...
Aim: In the radiation therapy, normal bone marrow is often included in radiation field inevitably. T...
Bone marrow is usually dose-limiting for radioimmunotherapy. In this study, we directly estimated re...
Red marrow is usually the dose-limiting organ during radioimmunotherapy. Several non-invasive approa...
Hematologic toxicity limits the radioactivity that may be administered for radiolabeled antibody the...
BACKGROUND: The method for red marrow dosimetry in radioimmunotherapy, in the absence of specific ac...
Noninvasive imaging techniques have been used in the past for visualization the functional activity ...
This study aimed to compare different image-based methods for bone marrow dosimetry and study the do...
Radiotherapy (RT) and chemotherapy are important treatment modalities for a variety of malignant tum...
Background Radiotherapy (RT) and chemotherapy are important treatment modalities for a variety of ma...
Calculated red marrow absorbed dose in patients receiving radioimmunotherapy (RAIT) has not been hig...
In the present study, we have measured bone marrow radioactivity using direct counting of tissues fr...
The aim of this work was the evaluation of the usefulness of 124I PET/CT sequential scans to predict...
Background: Red bone marrow (RBM) toxicity is dose-limiting in (pretargeted) radioimmunotherapy (RIT...
AIM: The aim of this work was the evaluation of the usefulness of 124I PET/CT sequential scans t...
Purpose: Adequate dosimetry is mandatory for effective and safe peptide receptor radionuclide therap...
Aim: In the radiation therapy, normal bone marrow is often included in radiation field inevitably. T...
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