Open Access GraProStr – Graphs of Protein Structures: A Tool for Constructing the Graphs and Generating Graph Parameters for Protein Structures

Abstract: Protein structures can be represented as graphs/networks by defining the amino-acids as nodes and the non-covalent interactions as connections (edges). An analysis of such a graph provides valuable insights into the global structural properties, function, folding, and stability of proteins. Here we have created a webtool GraProStr to generate protein structure networks and analyze network parameters. Protein side-chain based, C/C backbone based or protein-ligand Graphs/Networks can be generated using GraProStr. The well tested tool is now made available to the scientific community for the first time. GraProStr is available online and can be accessed fro