University Teaching Hospital, Lusaka Corresponding Author

Radiation Recall Dermatitis (RRD) is an acute inflammatory reaction that develops within an area of previous irradiation, occurring after administering a chemotherapeutic agent. We present the case of a 3-year-old Zambian girl with a nephroblastoma who developed radiation recall after the administration of dactinomycin, doxorubicin and vincristine. Our case attempts to highlight the importance of this rare condition. Given that radiotherapy and chemotherapy have such a close relationship in a multitude of cancers we feel it increasingly important to further understand this phenomenon and specifically its associations with certain drugs and susceptible individuals. To the best of our knowledge this is the first documented paediatric case of radiation recall from Zambia. BACKGROUND Radiation recall dermatitis was first described in 31958 when it was observed with dactinomycin. As most information comes from case reports pertaining to adults, it is not possible to determine the true incidence or prevalence The most frequent site of RRD is the skin but other reported involved organs include mucous membranes, lungs, oesophagus, gastrointestinal 1tract, central nervous system, bladder, and heart. A number of different drugs have been identified t