2001 Individualized model of human thermoregulation for the simulation of heat stress response

moregulation for the simulation of heat stress response. J Appl Physiol 90: 1943–1954, 2001. — A population-based dynamic model of human thermoregulation was expanded with control equations incorporating the individual person’s characteristics (body surface area, mass, fat%, maximal O2 uptake, acclima-tion). These affect both the passive (heat capacity, insulation) and active systems (sweating and skin blood flow function). Model parameters were estimated from literature data. Other data, collected for the study of individual differences {working at relative or absolute workloads in hot-dry [45°C, 20 % relative humidity (rh)], warm-humid [35°C, 80 % rh], and cool [21°C, 50 % rh] environments}, were used for validation. The individ-ualized model provides an improved prediction [mean core tem-perature error, 20.21 3 20.07°C (P, 0.001); mean squared error, 0.403 0.16°C, (P, 0.001)]. The magnitude of improve