Journal of Neurology, Neurosurgery, and Psychiatry 1982;45:802-808 Multiple sclerosis with clinical and radiological features of cerebral tumour

SUMMARY Three cases of multiple sclerosis, all confirmed pathologically, are described in whom both the unusual clinical features and the CIT scan appearances suggested cerebral tumours. The failure of mass effect reliably to differentiate plaques and tumours on a CT scan is stressed and the literature relating to CT scanning in multiple sclerosis is reviewed. "Cerebral " features, notably headache, epilepsy and aphasia are recognised but uncommon in multiple sclerosis and may suggest a diagnosis of cerebral tumour. ' Computed tomography of the head (CT scan) in multiple sclerosis has demonstrated enhanc-ing plaques which have been said to be distinguish-able from tumours by their lack of mass effect.26 We present three cases of "cerebral multiple sclerosis " in whom cerebral tumours were suspecte