www.impactjournals.com/oncotarget / Oncotarget, Vol. 6, No. 17 Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasm
Constitutive NOTCH signaling in lymphoid progenitors promotes the development of immature T-cell lym...
Notch is a signaling pathway involved in cellular growth and development. Aberrant activation of the...
Accumulating preclinical and clinical evidence supports a pro-oncogenic function for Notch signaling...
The immunosuppressive tumor microenvironment per-turbs numerous immune regulatory networks and usurp...
Proteasome inhibitors exert cytotoxicity and increase chemosensitivity via transcriptional repressio...
T-acute lymphoblastic leukemia (T-ALL) is characterized by several genetic alterations and poor prog...
Peripheral T-cell lymphomas (PTCL) are agressive lymphomas that develop from mature T cells. The mos...
An impaired antitumor immunity is found in patients with cancer and represents a major obstacle in t...
Notch receptors are transmembrane proteins critically determining cell fate and maintenance of proge...
Notch pathway plays a pivotal role in regulating cell proliferation, survival, differentiation and a...
Cancer immunotherapy, which stimulates or augments host immune responses to treat malignancies, is t...
The Notch pathway plays a key role in several processes, including stem-cell self-renewal, prolifera...
The identification of activating mutations in NOTCH1 in over 50 % of T-cell acute lymphoblastic leuk...
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological disease that arises from ...
The Notch pathway is frequently acti-vated in T-cell acute lymphoblastic leuke-mias (T-ALLs). Of the...
Constitutive NOTCH signaling in lymphoid progenitors promotes the development of immature T-cell lym...
Notch is a signaling pathway involved in cellular growth and development. Aberrant activation of the...
Accumulating preclinical and clinical evidence supports a pro-oncogenic function for Notch signaling...
The immunosuppressive tumor microenvironment per-turbs numerous immune regulatory networks and usurp...
Proteasome inhibitors exert cytotoxicity and increase chemosensitivity via transcriptional repressio...
T-acute lymphoblastic leukemia (T-ALL) is characterized by several genetic alterations and poor prog...
Peripheral T-cell lymphomas (PTCL) are agressive lymphomas that develop from mature T cells. The mos...
An impaired antitumor immunity is found in patients with cancer and represents a major obstacle in t...
Notch receptors are transmembrane proteins critically determining cell fate and maintenance of proge...
Notch pathway plays a pivotal role in regulating cell proliferation, survival, differentiation and a...
Cancer immunotherapy, which stimulates or augments host immune responses to treat malignancies, is t...
The Notch pathway plays a key role in several processes, including stem-cell self-renewal, prolifera...
The identification of activating mutations in NOTCH1 in over 50 % of T-cell acute lymphoblastic leuk...
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological disease that arises from ...
The Notch pathway is frequently acti-vated in T-cell acute lymphoblastic leuke-mias (T-ALLs). Of the...
Constitutive NOTCH signaling in lymphoid progenitors promotes the development of immature T-cell lym...
Notch is a signaling pathway involved in cellular growth and development. Aberrant activation of the...
Accumulating preclinical and clinical evidence supports a pro-oncogenic function for Notch signaling...