Alternative splicing is emerging as a major mech-anism for the expansion of the transcriptome and proteome diversity, particularly in human and other vertebrates. However, the proportion of alterna-tive transcripts and proteins actually endowed with functional activity is currently highly debated. We present here a new release of ASPicDB which now provides a unique annotation resource of human protein variants generated by alternative splicing. A total of 256 939 protein variants from 17 191 multi-exon genes have been extensively annotated through state of the art machine learn-ing tools providing information of the protein type (globular and transmembrane), localization
Alternative splicing (AS) generates remarkable regulatory and proteomic complexity in metazoans. How...
While the human genome was sequenced in 2001, its full annotation continues to be a challenging area...
Alternative splicing (AS) permits the synthesis of multiple transcript variants from a single gene i...
Alternative splicing is emerging as a major mech-anism for the expansion of the transcriptome and pr...
Alternative splicing is emerging as a major mech-anism for the expansion of the transcriptome and pr...
Alternative splicing is emerging as a major mechanism for the expansion of the transcriptome and pro...
Motivation: Alternative splicing has recently emerged as a key mechanism responsible for the expansi...
Motivation: Alternative splicing has recently emerged as a key mechanism responsible for the expansi...
Alternative splicing ( AS) is now emerging as a major mechanism contributing to the expansion of the...
Motivation: Alternative splicing has been suggested as a key mechanism for increasing the the functi...
Identification of proteins from proteolytic peptides or intact proteins plays an essential role in p...
We report the first genome-wide identification and characterization of alternative splicing in human...
Abstract Background Most human genes produce several transcripts with different exon contents by usi...
Alternative splicing is widespread in mammalian gene expression, and variant splice patterns are oft...
The degree of diversity at the transcriptome and proteome levels generated by alternative splicing i...
Alternative splicing (AS) generates remarkable regulatory and proteomic complexity in metazoans. How...
While the human genome was sequenced in 2001, its full annotation continues to be a challenging area...
Alternative splicing (AS) permits the synthesis of multiple transcript variants from a single gene i...
Alternative splicing is emerging as a major mech-anism for the expansion of the transcriptome and pr...
Alternative splicing is emerging as a major mech-anism for the expansion of the transcriptome and pr...
Alternative splicing is emerging as a major mechanism for the expansion of the transcriptome and pro...
Motivation: Alternative splicing has recently emerged as a key mechanism responsible for the expansi...
Motivation: Alternative splicing has recently emerged as a key mechanism responsible for the expansi...
Alternative splicing ( AS) is now emerging as a major mechanism contributing to the expansion of the...
Motivation: Alternative splicing has been suggested as a key mechanism for increasing the the functi...
Identification of proteins from proteolytic peptides or intact proteins plays an essential role in p...
We report the first genome-wide identification and characterization of alternative splicing in human...
Abstract Background Most human genes produce several transcripts with different exon contents by usi...
Alternative splicing is widespread in mammalian gene expression, and variant splice patterns are oft...
The degree of diversity at the transcriptome and proteome levels generated by alternative splicing i...
Alternative splicing (AS) generates remarkable regulatory and proteomic complexity in metazoans. How...
While the human genome was sequenced in 2001, its full annotation continues to be a challenging area...
Alternative splicing (AS) permits the synthesis of multiple transcript variants from a single gene i...