BACKGROUND

Solitary fibrous tumor (SFT), which usually presents in the pleura and is thought to be mesothelial in nature, has been recently discovered in extrapleural sites, including the orbit. Presently ultrastructural studies show absence of epithelial-mesothelial features, and reactivity of the tumor cells to CD34 antigen on immunohistochemical analysis suggests the mesenchymal origin of such tumors. CASE DESCRIPTION A 40-year-old woman had a 4-year history of progressive swelling of her right upper lid and a slow-growing palpa-ble mass of the orbit. CT and MR imaging showed a well circumscribed, nonenhanced extraconal mass with mild erosion of the right orbital roof. The tumor was totally excised. Histological examination disclosed a spindle-cell tumor in a dense fibrous tissue. Immunohistochemistry showed positive staining for vimentin and CD34. We re-view the clinical, diagnostic, and surgical features of 22 orbital SFTs including the present case. CONCLUSIONS Orbital SFT generally pursues a slow, indolent, and non-aggressive course, reaches a size up to 4.5 cm, and can be cured by a single excision. It must be immunohistochemi-cally differentiated from other spindle-cell tumors of th