The production of PET tracers for the diagnosis of oncological and neurological diseases

Positron emission tomography (PET) is a very sensitive method for the detection of pathophysiological processes on the molecular level. Radiotracers have to be designed, developed and synthesized capable to interact with molecular targets to exploit the potential of this method. Molecular targets mainly consist of enzymes or receptors overexpressed in diseased states like cancer or neurological disorders. The radiotracers specifically accumulate in these pathological regions indicating disease infiltration. These regions can be visualized by PET measurements delivering images of the 3D distribution of the radiotracer in vivo. The obtained PET scans deliver important diagnostic information and are essential for subsequent treatment planning.In this talk I will report about the design, radiosynthesis and application of PET tracers for diagnosis of neurological and oncological disorders