Two carp tumor necrosis factor alpha (TNF¿) genes have been cloned and sequenced. Both TNF1 and TNF2 sequences have several polymorphisms in the 3¿ UTR and TNF2 has a polymorphism in the coding sequence. Lipopolysaccharide and the protozoan blood flagellate Trypanoplasma borreli induced expression of TNF¿ in carp head kidney phagocytes when added in vitro. Differential expression was observed, with TNF2 being higher expressed than TNF1. We used the TNF¿-specific inhibitor pentoxifylline to demonstrate the involvement of carp TNF¿ in the induction of nitric oxide and in the stimulation of cell proliferation. In addition, two carp lines differing in their resistance to T. borreli were typed for the TNF2 polymorphism and association between on...
The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate innate immu...
Nile tilapia (Oreochromis niloticus) is a pivotal economic fish that has been plagued by Streptococc...
Tumour necrosis factor-alpha (TNF-a) is a key mediator of inflammation during amoebiasis of humans a...
Two carp tumor necrosis factor alpha (TNF¿) genes have been cloned and sequenced. Both TNF1 and TNF2...
Functional characterization of TNF- in species other than mammalian vertebrates is limited, and TNF-...
Interleukin-1beta (Il-1beta) is a central component in innate immunity and the inflammatory response...
Functional characterization of TNF-alpha in species other than mammalian vertebrates is limited, and...
Abstract Tumor necrosis factor receptor-associated factor 2 (TRAF2) is a crucial component of almost...
Tumour necrosis factor a (TNF-a) is a soluble cytokine that has a number of different roles in the i...
A tumor necrosis factor receptor-associated factor 2 binding protein (T2BP) gene was isolated from t...
In serum most of the iron molecules are bound to transferrin (Tf), which is a highly polymorphic pro...
Tumour necrosis factor α (TNF-α) is a soluble cytokine that has a number of different roles in the i...
The central role of transferrin (Tf) as an iron transporting protein has been extended by observatio...
BACKGROUND: In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer bet...
Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer be...
The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate innate immu...
Nile tilapia (Oreochromis niloticus) is a pivotal economic fish that has been plagued by Streptococc...
Tumour necrosis factor-alpha (TNF-a) is a key mediator of inflammation during amoebiasis of humans a...
Two carp tumor necrosis factor alpha (TNF¿) genes have been cloned and sequenced. Both TNF1 and TNF2...
Functional characterization of TNF- in species other than mammalian vertebrates is limited, and TNF-...
Interleukin-1beta (Il-1beta) is a central component in innate immunity and the inflammatory response...
Functional characterization of TNF-alpha in species other than mammalian vertebrates is limited, and...
Abstract Tumor necrosis factor receptor-associated factor 2 (TRAF2) is a crucial component of almost...
Tumour necrosis factor a (TNF-a) is a soluble cytokine that has a number of different roles in the i...
A tumor necrosis factor receptor-associated factor 2 binding protein (T2BP) gene was isolated from t...
In serum most of the iron molecules are bound to transferrin (Tf), which is a highly polymorphic pro...
Tumour necrosis factor α (TNF-α) is a soluble cytokine that has a number of different roles in the i...
The central role of transferrin (Tf) as an iron transporting protein has been extended by observatio...
BACKGROUND: In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer bet...
Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer be...
The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate innate immu...
Nile tilapia (Oreochromis niloticus) is a pivotal economic fish that has been plagued by Streptococc...
Tumour necrosis factor-alpha (TNF-a) is a key mediator of inflammation during amoebiasis of humans a...