A human exposure model to calculate harmonized risk limits - model description and analysis

The human exposure model, as integrated in the European risk assessment tool 'EUSES', lacks several exposure routes to contaminated soil that are part of the Dutch model 'CSOIL'. This report describes how the two models are combined into a new model, called 'Humanex'. This new model is aimed at calculating environmental concentrations for the protection of humans against hazardous effects of chemicals that can disperse into the environment. These concentrations, or so-called environmental risk limits, are based on a cumulative exposure of humans by way of water, soil, air and the diet. The model was analysed in a study on 17 compounds. Analysis showed that substance properties determine which of the potential exposure routes are most important for the total exposure. The study also revealed wich model components could still be improved