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CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence

Giona, Fiorina
Teofili, Luciana (ORCID:0000-0002-7214-1561)
Capodimonti, Sara
Laurino, Marica
Martini, Maurizio (ORCID:0000-0002-6260-6310)
Marzella, Deborah
Palumbo, Giovanna
Diverio, Daniela
Foa', Robin
Larocca, Luigi Maria (ORCID:0000-0003-1739-4758)

Publication date

January 2014

DOI

10.1182/blood-2014-04-572040

Publisher

American Society of Hematology

Abstract

CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescenc

Extracted data

Related items

High resolution melting analysis: a rapid and accurate method to detect CALR mutations.

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CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescenc

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After the recent discovery of various mutations of theCALRgene,,10% of adult patients with essential...

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CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles.

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Guillermo Santana
Melania Moreno
Laura Torres
Gonzalo Santana-Lopez
Carlos Rodriguez-Medina
María Perera
Beatriz Bellosillo
Silvia de la Iglesia
Teresa Molero
Maria Teresa Gomez-Casares

The recent discovery of CALR mutations in essential thrombocythemia (ET) and primary myelofibrosis (...

CALR mutation profile in Irish patients with myeloproliferative neoplasms

Haslam, Karl
Conneally, Eibhlin
Flynn, Catherine M.
Cahill, Mary R.
Gilligan, Oonagh
O’Shea, Derville
Langabeer, Stephen E.

September 2016

AbstractInsertion and/or deletion mutations of the CALR gene have recently been demonstrated to be t...

Effects of <i>CALR</i>-Mutant Type and Burden on the Phenotype of Myeloproliferative Neoplasms

Hyun-Young Kim
Yujin Han
Jun Ho Jang
Chul Won Jung
Sun-Hee Kim
Hee-Jin Kim

October 2022

Somatic CALR mutations occur in approximately 70% of patients with JAK2 V617F-negative essential thr...

CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence

Teofili, Luciana (ORCID:0000-0002-7214-1561)
Capodimonti, Sara
Martini, Maurizio (ORCID:0000-0002-6260-6310)
Larocca, Luigi Maria (ORCID:0000-0003-1739-4758)

January 2014

CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescenc

CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence.

GIONA, Fiorina
Teofili L
Capodimonti S
Laurino M
Martini M
Marzella D
Palumbo G
Diverio D
FOA, Roberto
Larocca L.M.

January 2014

After the recent discovery of various mutations of theCALRgene,,10% of adult patients with essential...

Analysis of Phenotype and Outcome in Essential Thrombocythemia with CALR or JAK2 mutations

Al Assaf, Carla
Van Obbergh, Florence
Billiet, Johan
Lierman, Els
Devos, Timothy
Graux, Carlos
Hervent, Anne-Sophie
Emmerechts, Jan
Tousseyn, Thomas
De Paepe, Pascale
Papadopoulos, Petros
Michaux, Lucienne
Vandenberghe, Peter

July 2015

The JAK2 V617F mutation, the thrombopoietin receptor MPL W515K/L mutation and the Calreticulin (CALR...

Analysis of phenotype and outcome in essential thrombocythemia with CALR or JAK2 mutations.

Al Assaf, Carla
Van Obbergh, Florence
Billiet, Johan
Lierman, Els
Devos, Timothy
Graux, Carlos
Hervent, Anne-Sophie
Emmerechts, Jan
Tousseyn, Thomas
De Paepe, Pascale
Papadopoulos, Petros
Michaux, Lucienne
Vandenberghe, Peter

January 2015

The JAK2 V617F mutation, the thrombopoietin receptor MPL W515K/L mutation and calreticulin (CALR) mu...

CALR exon 9 mutations are somatically acquired events in familial cases of essential thrombocythemia or primary myelofibrosis

RUMI, ELISA
Harutyunyan AS
Pietra D
Milosevic JD
Casetti IC
Bellini M
Them NC
Cavalloni C
Ferretti VV
Milanesi C
Berg T
Sant'Antonio E
Boveri E
Pascutto C
Astori C
Kralovics R
CAZZOLA, MARIO

January 2014

Somatic mutations in the calreticulin (CALR) gene were recently discovered in patients with sporadic...

Type 1 versus Type 2 calreticulin mutations in essential thrombocythemia: A collaborative study of 1027 patients

Tefferi, A.
Wassie, E. A.
Guglielmelli, P.
Gangat, N.
Belachew, A. A.
Lasho, T. L.
Finke, C.
Ketterling, R. P.
Hanson, C. A.
Pardanani, A.
Wolanskyj, A. P.
Maffioli, M.
Casalone, R.
Pacilli, A.
Vannucchi, A. M.
PASSAMONTI, FRANCESCO

January 2014

CALR (calreticulin) trails JAK2 as the second most mutated gene in essential thrombocythemia (ET). M...

Mutant CALR functions: gains and losses.

Prins, Daniel
Green, Tony

July 2020

In this issue of Blood, Shide et al separate the roles of loss of a normal CALR allele and gain of a...

JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes.

RUMI, ELISA
ELENA, CHIARA
CAZZOLA, MARIO
Pietra, D
Ferretti, V
Klampfl, T
Harutyunyan, As
Milosevic, Jd
Them, Nc
Berg, T
Casetti, Ic
Milanesi, C
Sant'Antonio, E
Bellini, M
Fugazza, E
Renna, Mc
Boveri, E
Astori, C
Pascutto, C
Kralovics, R

January 2014

Patients with essential thrombocythemia may carry JAK2 (V617F), an MPL substitution, or a calreticul...

Somatic calreticulin mutations in patients with Budd-Chiari syndrome and portal vein thrombosis

Plompen, Elisabeth P.C.
Valk, Peter J.M.
Chu, Isabel
Murad, Sarwa D.
Plessier, Aurelie
Turon, Fanny
Trebicka, Jonel
Primignani, Massimo
García Pagán, Juan Carlos
Valla, Dominique
Janssen, Harry L.A.
Leebeek, Frank W.G.

Carta a l'editorWe studied the role of the recently identified CALR mutations in 141 patients with B...

CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles.

Zini R
Guglielmelli P
Pietra D
Rumi E
Rossi C
Rontauroli S
Genovese E
Fanelli T
Calabresi L
Bianchi E
Salati S
Cazzola M
Tagliafico E
Vannucchi AM
Manfredini R

January 2017

Polycythemia vera (PV) and essential thrombocythemia (ET) are Philadelphia-negative myeloproliferati...

Clinical Manifestation of Calreticulin Gene Mutations in Essential Thrombocythemia without Janus Kinase 2 and MPL Mutations: A Chinese Cohort Clinical Study

Chao Sun
Xin Zhou
Zhi-Jian Zou
Hong-Feng Guo
Jian-Yong Li
Chun Qiao

January 2016

Background: Recently, calreticulin (CALR) gene mutations have been identified in patients with essen...

CALR mutation profile in Irish patients with myeloproliferative neoplasms

Haslam, Karl
Conneally, Eibhlin
Flynn, Catherine M.
Cahill, Mary R.
Gilligan, Oonagh
O\u27Shea, Derville
Langabeer, Stephen E.

June 2016

Insertion and/or deletion mutations of the CALR gene have recently been demonstrated to be the secon...

High resolution melting analysis: a rapid and accurate method to detect CALR mutations.

Cristina Bilbao-Sieyro
Guillermo Santana
Melania Moreno
Laura Torres
Gonzalo Santana-Lopez
Carlos Rodriguez-Medina
María Perera
Beatriz Bellosillo
Silvia de la Iglesia
Teresa Molero
Maria Teresa Gomez-Casares

The recent discovery of CALR mutations in essential thrombocythemia (ET) and primary myelofibrosis (...

CALR mutation profile in Irish patients with myeloproliferative neoplasms

Haslam, Karl
Conneally, Eibhlin
Flynn, Catherine M.
Cahill, Mary R.
Gilligan, Oonagh
O’Shea, Derville
Langabeer, Stephen E.

September 2016

AbstractInsertion and/or deletion mutations of the CALR gene have recently been demonstrated to be t...

Effects of <i>CALR</i>-Mutant Type and Burden on the Phenotype of Myeloproliferative Neoplasms

Hyun-Young Kim
Yujin Han
Jun Ho Jang
Chul Won Jung
Sun-Hee Kim
Hee-Jin Kim

October 2022

Somatic CALR mutations occur in approximately 70% of patients with JAK2 V617F-negative essential thr...