Metal–organic framework coatings as cytoprotective exoskeletons for living cells
- Liang, K.
- Richardson, J.
- Cui, J.
- Caruso, F.
- Doonan, C.
- Falcaro, P.
Publication date
January 2016
DOI Publisher
Wiley ISSN
0935-9648 Journal
Advanced Materials Citation count (estimate)
26Abstract
The biomimetic mineralization of metal–organic framework (MOF) material on living cells is reported. ZIF-8 can be crystallized on a living cell surface as an exoskeleton that offers physical protection while allowing transport of essential nutrients, thus maintaining cell viability. The MOF shell prevents cell division, leading to an artificially induced pseudo-hibernation state. Cellular functions can be fully restored upon MOF removal.Kang Liang, Joseph J. Richardson, Jiwei Cui, Frank Caruso, Christian J. Doonan and Paolo Falcar
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