Published online: 21 April 2015Ovarian cancer, the most lethal gynaecological cancer, is characterised by the shedding of epithelial cells from the ovarian surface, followed by metastasis and implantation onto the peritoneal surfaces of abdominal organs. Our proteomic studies investigating the interactions between peritoneal (LP-9) and ovarian cancer (OVCAR-5) cells found transketolase (TKT) to be regulated in the co-culture system. This study characterized TKT expression in advanced stage (III/IV) serous ovarian cancers (n = 125 primary and n = 54 peritoneal metastases), normal ovaries (n = 6) and benign serous cystadenomas (n = 10) by immunohistochemistry. In addition, we also evaluated the function of TKT in ovarian cancer cells in vitro...
Purpose: The aim of this study was to investigate the role of pericytes in regulating malignant ovar...
Ovarian cancer is one of the deadliest women malignancies in the world. The chemoresistance accompan...
[[abstract]]Although metabolic reprogramming is recognized as a hallmark of tumorigenesis and progre...
Abstract Background Tumor cells need large energy and nucleic acids to proliferate and grow. For mos...
Published online: 17 September 2013Ovarian cancer, in particular epithelial ovarian cancer (EOC), is...
Ovarian cancer is an intra-abdominal tumor accompanied with the presence of ascites for metastatic d...
Ovarian cancer metastasis is characterized by the shedding of malignant cells from the surface of th...
We show that atypical PKCiota, which plays a critical role in the establishment and maintenance of e...
Ovarian cancer (OvCa) is the leading cause of death among gynecological malignancies, and is charact...
International audienceBACKGROUND:The microenvironment plays a major role in the onset and progressio...
Peritoneal dissemination is a particular form of metastasis typically observed in ovarian cancer and...
Session 4: Organismal MetabolismOvarian cancer is an intra-abdominal tumor in which the presence of ...
Ovarian cancer metastasis is characterized by the shedding of malignant cells from the surface of th...
PURPOSE: The aim of this study was to investigate the role of pericytes in regulating malignant ovar...
Introduction: Aberrant levels of kallikrein-related peptidases (KLK1-15) have been linked to cancer ...
Purpose: The aim of this study was to investigate the role of pericytes in regulating malignant ovar...
Ovarian cancer is one of the deadliest women malignancies in the world. The chemoresistance accompan...
[[abstract]]Although metabolic reprogramming is recognized as a hallmark of tumorigenesis and progre...
Abstract Background Tumor cells need large energy and nucleic acids to proliferate and grow. For mos...
Published online: 17 September 2013Ovarian cancer, in particular epithelial ovarian cancer (EOC), is...
Ovarian cancer is an intra-abdominal tumor accompanied with the presence of ascites for metastatic d...
Ovarian cancer metastasis is characterized by the shedding of malignant cells from the surface of th...
We show that atypical PKCiota, which plays a critical role in the establishment and maintenance of e...
Ovarian cancer (OvCa) is the leading cause of death among gynecological malignancies, and is charact...
International audienceBACKGROUND:The microenvironment plays a major role in the onset and progressio...
Peritoneal dissemination is a particular form of metastasis typically observed in ovarian cancer and...
Session 4: Organismal MetabolismOvarian cancer is an intra-abdominal tumor in which the presence of ...
Ovarian cancer metastasis is characterized by the shedding of malignant cells from the surface of th...
PURPOSE: The aim of this study was to investigate the role of pericytes in regulating malignant ovar...
Introduction: Aberrant levels of kallikrein-related peptidases (KLK1-15) have been linked to cancer ...
Purpose: The aim of this study was to investigate the role of pericytes in regulating malignant ovar...
Ovarian cancer is one of the deadliest women malignancies in the world. The chemoresistance accompan...
[[abstract]]Although metabolic reprogramming is recognized as a hallmark of tumorigenesis and progre...