International audienceWith the aim to develop biomaterials for temporary medical devices, a series of novel reducible and/or degradable elastomers has been prepared from PLA-b-PEG-b-PLA copolymers photo-crosslinked with diallyl sulfide or pentaerythritol tetrakis(3-mercaptopropionate). Thermal and mechanical properties, including elastic limit and Young modulus, are assessed. Degradation is then evaluated under standard hydrolytic conditions. Reducibility of a selected elastomer is then illustrated using 2-mercaptoethanol or glutathione as reducing agents. The redox-sensitivity of the selected elastomer and the possibility to modulate the degradability are shown. Considering drug-eluting elastomeric devices applications, anti-inflammatory d...
Richard Song,1 Maxwell Murphy,1 Chenshuang Li,1 Kang Ting,1–3 Chia Soo,2 Zhong Zheng1 1Divisi...
Polymers that are biocompatible and degrade in response to stimuli are highly desirable as smart dru...
Biodegradable Thermoplastic Elastomer (BTPE) has the potential uses as implantable devices due to th...
Biodegradable elastomers have attracted a great deal of interest due to their potential applications...
YesComplex biological tissues are highly viscoelastic and dynamic. Efforts to repair or replace cart...
Synthetic biodegradable polymers are of great value for the preparation of implants that are require...
For polymer-based degradable implants, mechanical performance and degradation behavior need to be pr...
Elastomeric scaffolds play an important role in the field of soft tissue engineering, and recently, ...
Degradable bioelastomers are novel polymer biomaterials mainly applied in soft tissue engineering an...
There is a need for biodegradable thermoplastic elastomers for a variety of medical applications. Th...
Injectable materials often have shortcomings in mechanical and drug-eluting properties that are attr...
Although biodegradable polymers have found extensive application in medical devices, there are very ...
This article reviews the degradability of chemically synthesized bioelastomers, mainly designed for ...
Development of modern medical technologies would be impossible without the application of various ma...
In the last half-century, the development of biodegradable polymeric materials for biomedical applic...
Richard Song,1 Maxwell Murphy,1 Chenshuang Li,1 Kang Ting,1–3 Chia Soo,2 Zhong Zheng1 1Divisi...
Polymers that are biocompatible and degrade in response to stimuli are highly desirable as smart dru...
Biodegradable Thermoplastic Elastomer (BTPE) has the potential uses as implantable devices due to th...
Biodegradable elastomers have attracted a great deal of interest due to their potential applications...
YesComplex biological tissues are highly viscoelastic and dynamic. Efforts to repair or replace cart...
Synthetic biodegradable polymers are of great value for the preparation of implants that are require...
For polymer-based degradable implants, mechanical performance and degradation behavior need to be pr...
Elastomeric scaffolds play an important role in the field of soft tissue engineering, and recently, ...
Degradable bioelastomers are novel polymer biomaterials mainly applied in soft tissue engineering an...
There is a need for biodegradable thermoplastic elastomers for a variety of medical applications. Th...
Injectable materials often have shortcomings in mechanical and drug-eluting properties that are attr...
Although biodegradable polymers have found extensive application in medical devices, there are very ...
This article reviews the degradability of chemically synthesized bioelastomers, mainly designed for ...
Development of modern medical technologies would be impossible without the application of various ma...
In the last half-century, the development of biodegradable polymeric materials for biomedical applic...
Richard Song,1 Maxwell Murphy,1 Chenshuang Li,1 Kang Ting,1–3 Chia Soo,2 Zhong Zheng1 1Divisi...
Polymers that are biocompatible and degrade in response to stimuli are highly desirable as smart dru...
Biodegradable Thermoplastic Elastomer (BTPE) has the potential uses as implantable devices due to th...