The work described in this thesis is concerned with mechanisms of contact lens lubrication. There are three major driving forces in contact lens design and development; cost, convenience, and comfort. Lubrication, as reflected in the coefficient of friction, is becoming recognised as one of the major factors affecting the comfort of the current generation of contact lenses, which have benefited from several decades of design and production improvements. This work started with the study of the in-eye release of soluble macromolecules from a contact lens matrix. The vehicle for the study was the family of CIBA Vision Focus® DAILIES® daily disposable contact lenses which is based on polyvinyl alcohol (PVA). The effective release of linear solu...
[[abstract]]The ocular discomfort is the leading cause of contact lens wear discontinuation. Althoug...
Feeling comfortable is the greatest concern for contact lens wearers, and it has been suggested that...
[[abstract]]Feeling comfortable is the greatest concern for contact lens wearers, and it has been su...
Millions of contact lens wearers suffer from eye irritation due to dry eye disease (DED), which is m...
The soft contact lenses of today are made from a variety of hydrogel materials. These materials have...
The irritation/discomfort associated with the use of contact lenses (CLs) is often related to the ey...
The thesis investigates the ocular response to silicone-hydrogel (SiH) contact lens wear, a relative...
The thesis investigates the ocular response to silicone-hydrogel (SiH) contact lens wear, a relative...
[[abstract]]When a contact lens is in contact with the eyelid and the cornea, tear proteins start to...
[[abstract]]When a contact lens is in contact with the eyelid and the cornea, tear proteins start to...
[[abstract]]When a contact lens is in contact with the eyelid and the cornea, tear proteins start to...
Background: At the ocular surface, epithelial cells are subject to shear and frictionforces during b...
[[abstract]]Feeling comfortable is the greatest concern for contact lens wearers, and it has been su...
[[abstract]]The ocular discomfort is the leading cause of contact lens wear discontinuation. Althoug...
[[abstract]]The ocular discomfort is the leading cause of contact lens wear discontinuation. Althoug...
[[abstract]]The ocular discomfort is the leading cause of contact lens wear discontinuation. Althoug...
Feeling comfortable is the greatest concern for contact lens wearers, and it has been suggested that...
[[abstract]]Feeling comfortable is the greatest concern for contact lens wearers, and it has been su...
Millions of contact lens wearers suffer from eye irritation due to dry eye disease (DED), which is m...
The soft contact lenses of today are made from a variety of hydrogel materials. These materials have...
The irritation/discomfort associated with the use of contact lenses (CLs) is often related to the ey...
The thesis investigates the ocular response to silicone-hydrogel (SiH) contact lens wear, a relative...
The thesis investigates the ocular response to silicone-hydrogel (SiH) contact lens wear, a relative...
[[abstract]]When a contact lens is in contact with the eyelid and the cornea, tear proteins start to...
[[abstract]]When a contact lens is in contact with the eyelid and the cornea, tear proteins start to...
[[abstract]]When a contact lens is in contact with the eyelid and the cornea, tear proteins start to...
Background: At the ocular surface, epithelial cells are subject to shear and frictionforces during b...
[[abstract]]Feeling comfortable is the greatest concern for contact lens wearers, and it has been su...
[[abstract]]The ocular discomfort is the leading cause of contact lens wear discontinuation. Althoug...
[[abstract]]The ocular discomfort is the leading cause of contact lens wear discontinuation. Althoug...
[[abstract]]The ocular discomfort is the leading cause of contact lens wear discontinuation. Althoug...
Feeling comfortable is the greatest concern for contact lens wearers, and it has been suggested that...
[[abstract]]Feeling comfortable is the greatest concern for contact lens wearers, and it has been su...