International audienceSirvent et al1 recently showed that novel vaccines targeting dendritic cells (DCs) by coupling glutaraldehyde-polymerized grass pollen allergoids to nonoxidized mannan enhance allergen uptake and induce functional regulatory T cells through programmed death ligand 1. Mechanistically, they found that nonoxidized mannan-coupled glutaraldehyde-polymerized grass pollen allergoids are captured and internalized by 2 lectin receptors on DCs: mannose receptor (CD206) and DC-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN or CD209). These data thus indicated that DCs could be targeted by C-type lectin receptors for efficient allergen immunotherapy
Dendritic cells (DCs) are crucial in determining the functional outcome of allergen encounter in the...
Dendritic cells (DCs) have been shown to play a key role in the initiation and maintenance of immune...
Dendritic cells (DC) are present in essentially every tissue, where they operate at the interface of...
Allergic diseases currently affect a third of the population in the industrialized parts of the worl...
Basophils are emerging as immunoregulatory cells capable of interacting with their environment not o...
The immune system has evolved to protect the human body against harmful invaders. At the same time, ...
Background: Dendritic cells (DCs) are key players in the induction and re-elicitation of TH2 respons...
Allergen-specific immunotherapy (AIT) induces tolerance and shifts the Th2 response towards a regula...
Contains fulltext : 69700.pdf (Publisher’s version ) (Open Access)The fungus Candi...
Dendritic cells (DCs) have been shown to play a key role in the initiation and maintenance of immune...
Glycodendropeptides (GDPs) functionalized with mannose can enhance allergen interaction with dendrit...
Dendritic cells are crucial in determining the functional outcome of allergen encounter in the lung....
The fungus Candida albicans is the most common cause of mycotic infections in immunocompromised host...
Dendritic cells are crucial in determining the functional outcome of allergen encounter in the lung....
The mannose receptor (MR) /CD206 is a 175 kDa C-type lectin of type I, with 8 carbohydrate recogniti...
Dendritic cells (DCs) are crucial in determining the functional outcome of allergen encounter in the...
Dendritic cells (DCs) have been shown to play a key role in the initiation and maintenance of immune...
Dendritic cells (DC) are present in essentially every tissue, where they operate at the interface of...
Allergic diseases currently affect a third of the population in the industrialized parts of the worl...
Basophils are emerging as immunoregulatory cells capable of interacting with their environment not o...
The immune system has evolved to protect the human body against harmful invaders. At the same time, ...
Background: Dendritic cells (DCs) are key players in the induction and re-elicitation of TH2 respons...
Allergen-specific immunotherapy (AIT) induces tolerance and shifts the Th2 response towards a regula...
Contains fulltext : 69700.pdf (Publisher’s version ) (Open Access)The fungus Candi...
Dendritic cells (DCs) have been shown to play a key role in the initiation and maintenance of immune...
Glycodendropeptides (GDPs) functionalized with mannose can enhance allergen interaction with dendrit...
Dendritic cells are crucial in determining the functional outcome of allergen encounter in the lung....
The fungus Candida albicans is the most common cause of mycotic infections in immunocompromised host...
Dendritic cells are crucial in determining the functional outcome of allergen encounter in the lung....
The mannose receptor (MR) /CD206 is a 175 kDa C-type lectin of type I, with 8 carbohydrate recogniti...
Dendritic cells (DCs) are crucial in determining the functional outcome of allergen encounter in the...
Dendritic cells (DCs) have been shown to play a key role in the initiation and maintenance of immune...
Dendritic cells (DC) are present in essentially every tissue, where they operate at the interface of...