International audienceChemotherapies allow complete remission in more than 50 % of patients with acute myeloid leukemia (AML), however, with frequent relapse. This suggests that residual leukemic cells may escape to chemotherapy and immune system. Natural killer (NK) cells from AML patients (AML-NK) have a weaker natural cytotoxicity-activating receptors (NCRs) expression than NK cells from healthy donors (HD-NK). Coding genes for NCR1/NKp46, NCR2/NKp44 and NCR3/NKp30 are located at different loci on two different chromosomes; however, their expression is tightly coordinated. Most NK cells express either high (NCRbright) or low levels (NCRdull) of all three NCRs. This suggests the existence of negative/positive regulation factor(s) common t...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceChemotherapies allow complete remission in more than 50 % of patients with acu...
International audienceChemotherapies allow complete remission in more than 50 % of patients with acu...
Despite successful induction chemotherapy, most patients with acute myeloid leukemia (AML) will rel...
Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in...
The majority of patients with acute myeloid leukemia will relapse, and older patients often fail to ...
Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceChemotherapies allow complete remission in more than 50 % of patients with acu...
International audienceChemotherapies allow complete remission in more than 50 % of patients with acu...
Despite successful induction chemotherapy, most patients with acute myeloid leukemia (AML) will rel...
Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in...
The majority of patients with acute myeloid leukemia will relapse, and older patients often fail to ...
Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
Introduction: Acute myeloid leukemia (AML) is associated with heterogeneous cytogenetic abnormalitie...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...
International audienceNK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we ...