DNA damage and transcription are two interconnected events. Transcription can induce damage and scheduled DNA damage can be required for transcription. Here, we analyzed genome-wide distribution of 8oxodG-marked oxidative DNA damage obtained by OxiDIP-Seq, and we found a correlation with transcription of protein coding genes
L’activation d’oncogènes entraine une prolifération aberrante des cellules, un stress réplicatif et ...
DNA is exposed to chemical and physical agents that represent a continuous threat to its integrity b...
Resumen del trabajo presentado a la Conferencia Dynamic DNA Structure in Biology, celebrada en Saxto...
Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and ...
Tese de doutoramento, Ciências Biomédicas (Biologia Celular e Molecular), Universidade de Lisboa, Fa...
Errors in DNA that occur during replication serve as the basis for adaptation and heritable genetic ...
Genome replication involves dealing with obstacles that can result from DNA damage but also from ch...
The integrity of DNA is continuously challenged by genotoxic insults from both endogenous and exogen...
Since the thesis that every gene acts as a single unit which transcription is solely regulated by pr...
These results indicate a role of the Rad7 E3 ubiquitin ligase in regulation of cellular dNTP levels ...
Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and ...
AbstractCellular systems for DNA repair ensure prompt removal of DNA lesions that threaten the genom...
Cellular genomes are vulnerable to an array of DNA-damaging agents, of both endogenous and environme...
Genome replication involves dealing with obstacles that can result from DNA damage but also from chr...
textSurvival of cells and organisms requires that each of thousands of genes is expressed at the cor...
L’activation d’oncogènes entraine une prolifération aberrante des cellules, un stress réplicatif et ...
DNA is exposed to chemical and physical agents that represent a continuous threat to its integrity b...
Resumen del trabajo presentado a la Conferencia Dynamic DNA Structure in Biology, celebrada en Saxto...
Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and ...
Tese de doutoramento, Ciências Biomédicas (Biologia Celular e Molecular), Universidade de Lisboa, Fa...
Errors in DNA that occur during replication serve as the basis for adaptation and heritable genetic ...
Genome replication involves dealing with obstacles that can result from DNA damage but also from ch...
The integrity of DNA is continuously challenged by genotoxic insults from both endogenous and exogen...
Since the thesis that every gene acts as a single unit which transcription is solely regulated by pr...
These results indicate a role of the Rad7 E3 ubiquitin ligase in regulation of cellular dNTP levels ...
Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and ...
AbstractCellular systems for DNA repair ensure prompt removal of DNA lesions that threaten the genom...
Cellular genomes are vulnerable to an array of DNA-damaging agents, of both endogenous and environme...
Genome replication involves dealing with obstacles that can result from DNA damage but also from chr...
textSurvival of cells and organisms requires that each of thousands of genes is expressed at the cor...
L’activation d’oncogènes entraine une prolifération aberrante des cellules, un stress réplicatif et ...
DNA is exposed to chemical and physical agents that represent a continuous threat to its integrity b...
Resumen del trabajo presentado a la Conferencia Dynamic DNA Structure in Biology, celebrada en Saxto...