Mitotic exit and cytokinesis are driven by a complex set of processes that serve to reset the eukaryotic cell cycle and allow entry into the subsequent cycle. These steps are driven by a combination of molecular events that lead to the termination of high cyclin dependent kinase (Cdk) activity and reversal of Cdk mediated phosphorylation. Proteasomal degradation of cyclins is essential for terminating Cdk activity and active dephosphorylation of Cdk mediated phosphorylation is important for the appropriate completion of the cell cycle. The anaphase promoting complex (APC) is a ubiquitin ligase responsible for promoting events in late mitosis by polyubiquitinating, among other substrates, cyclins and targeting them for degradation. Cdh1 is a...
The CDC14 gene of Saccharomyces cerevisiae encodes an oligomeric dual specificity phosphatase whose ...
In eukaryotes, the two major cell cycle events of DNA replication and chromosome segregation are dir...
Cdc14 is a protein phosphatase from budding yeast whose activity is required for cells to end mitosi...
Cdc14 enzymes compose a family of highly conserved phosphatases that are present in a wide range of ...
Inactivation of cyclin-dependent kinase (Cdk) and reversal of Cdk phosphorylation are universally re...
Entry into mitosis of the eukaryotic cell cycle is driven by rising cyclin-dependent kinase (Cdk) ac...
The anaphase-promoting complex (APC) is a highly conserved ubiquitin ligase that regulates chromosom...
This article belongs to the Special Issue Protein Phosphatases and Cell Cycle Regulation in Yeasts.T...
Cdc14 phosphatase regulates multiple events during an-aphase and is essential for mitotic exit in bu...
In Eukaryotes, cell cycle-dependent protein proteolysis is a hallmark of the cell cycle and is media...
Mitotic exit depends on the proper degradation of numerous cell cycle-regulated proteins, which is e...
Metaphase of mitosis is brought about in all eukaryotes by activation of cylin-dependent kinase (Cdk...
The Cdc14 phosphatase is a key regulator of mitosis in the budding yeast Saccharomyces cerevisiae. C...
An association with the protein Net1 controls Cdc14 regulation in budding yeast. Net1 is a competiti...
Degradation of the M phase cyclins triggers the exit from M phase. Cdc14 is the major phosphatase re...
The CDC14 gene of Saccharomyces cerevisiae encodes an oligomeric dual specificity phosphatase whose ...
In eukaryotes, the two major cell cycle events of DNA replication and chromosome segregation are dir...
Cdc14 is a protein phosphatase from budding yeast whose activity is required for cells to end mitosi...
Cdc14 enzymes compose a family of highly conserved phosphatases that are present in a wide range of ...
Inactivation of cyclin-dependent kinase (Cdk) and reversal of Cdk phosphorylation are universally re...
Entry into mitosis of the eukaryotic cell cycle is driven by rising cyclin-dependent kinase (Cdk) ac...
The anaphase-promoting complex (APC) is a highly conserved ubiquitin ligase that regulates chromosom...
This article belongs to the Special Issue Protein Phosphatases and Cell Cycle Regulation in Yeasts.T...
Cdc14 phosphatase regulates multiple events during an-aphase and is essential for mitotic exit in bu...
In Eukaryotes, cell cycle-dependent protein proteolysis is a hallmark of the cell cycle and is media...
Mitotic exit depends on the proper degradation of numerous cell cycle-regulated proteins, which is e...
Metaphase of mitosis is brought about in all eukaryotes by activation of cylin-dependent kinase (Cdk...
The Cdc14 phosphatase is a key regulator of mitosis in the budding yeast Saccharomyces cerevisiae. C...
An association with the protein Net1 controls Cdc14 regulation in budding yeast. Net1 is a competiti...
Degradation of the M phase cyclins triggers the exit from M phase. Cdc14 is the major phosphatase re...
The CDC14 gene of Saccharomyces cerevisiae encodes an oligomeric dual specificity phosphatase whose ...
In eukaryotes, the two major cell cycle events of DNA replication and chromosome segregation are dir...
Cdc14 is a protein phosphatase from budding yeast whose activity is required for cells to end mitosi...