Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer.
- Bense, Rico RD
- Sotiriou, Christos
- Piccart-Gebhart, Martine
- Haanen, John B A G JB
- van Vugt, Marcel A T M MA
- de Vries, Elisabeth Ge E Liesbeth E.
- Schröder, Carolien P
- Fehrmann, Rudolf RS
Publication date
October 2016
DOI Publisher
Oxford University Press (OUP) ISSN
0027-8874 Citation count (estimate)
18Abstract
Not all breast cancer patients benefit from neoadjuvant or adjuvant therapy, resulting in considerable undertreatment or overtreatment. New insights into the role of tumor-infiltrating immune cells suggest that their composition, as well as their functionality, might serve as a biomarker to enable optimal patient selection for current systemic therapies and upcoming treatment options such as immunotherapy.SCOPUS: re.jinfo:eu-repo/semantics/publishe
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