Molecular profiling of thousands of primary breast cancers has uncovered remarkable genomic diversity between breast cancer subtypes, and even within subtypes. Only a few driver genes are recurrently altered at high frequency highlighting great challenges for precision medicine. Considerable evidence also confirms the role of host immunosurveillance in influencing response to therapy and prognosis in HER2+ and triple negative breast cancer. The role of immunosurveillance in ER + disease remains unclear. Advances in both these fields have lead to intensified interest in the interaction between genomic landscapes and host anti-tumour immune responses in breast cancer. In this review, we discuss the potential genomic determinants of host anti-...
Abstract The biology of breast cancer response to neoadjuvant therapy is underrepresented in the lit...
In cancer immunology, somatic missense mutations have been mostly studied with regard to their role ...
Cancer is a complex and heterogeneous disease that can sometimes be effectively targeted with precis...
The presence of tumor-infiltrating lymphocytes (TIL) is a favorable prognostic factor in breast canc...
International audienceCancer immunotherapy is revolutionizing the clinical management of several tum...
11 p.-6 fig.Identification of genomic alterations that influence the immune response within the tumo...
Heterogeneity of triple-negative breast cancer is well known at clinical, histopathological, and mol...
Breast cancer is characterized by some types of heterogeneity, high aggressive behaviour, and low im...
Breast cancer is characterized by some types of heterogeneity, high aggressive behaviour, and low im...
Breast cancer is the most common malignancy among females in western countries, where women have an ...
There is an increasing awareness of the importance of tumor – immune cell interactions to the evolut...
Breast cancer is characterized by some types of heterogeneity, high aggressive behaviour, and low im...
The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature a...
The genomic landscape of breast cancer is complex, and inter- and intra-tumour heterogeneity are imp...
Background: The aim of this paper was to identify an immunotherapy-sensitive subtype for estrogen re...
Abstract The biology of breast cancer response to neoadjuvant therapy is underrepresented in the lit...
In cancer immunology, somatic missense mutations have been mostly studied with regard to their role ...
Cancer is a complex and heterogeneous disease that can sometimes be effectively targeted with precis...
The presence of tumor-infiltrating lymphocytes (TIL) is a favorable prognostic factor in breast canc...
International audienceCancer immunotherapy is revolutionizing the clinical management of several tum...
11 p.-6 fig.Identification of genomic alterations that influence the immune response within the tumo...
Heterogeneity of triple-negative breast cancer is well known at clinical, histopathological, and mol...
Breast cancer is characterized by some types of heterogeneity, high aggressive behaviour, and low im...
Breast cancer is characterized by some types of heterogeneity, high aggressive behaviour, and low im...
Breast cancer is the most common malignancy among females in western countries, where women have an ...
There is an increasing awareness of the importance of tumor – immune cell interactions to the evolut...
Breast cancer is characterized by some types of heterogeneity, high aggressive behaviour, and low im...
The biology of breast cancer response to neoadjuvant therapy is underrepresented in the literature a...
The genomic landscape of breast cancer is complex, and inter- and intra-tumour heterogeneity are imp...
Background: The aim of this paper was to identify an immunotherapy-sensitive subtype for estrogen re...
Abstract The biology of breast cancer response to neoadjuvant therapy is underrepresented in the lit...
In cancer immunology, somatic missense mutations have been mostly studied with regard to their role ...
Cancer is a complex and heterogeneous disease that can sometimes be effectively targeted with precis...