The role of biochemical of bone turnover markers in osteoporosis and metabolic bone disease: a consensus paper of the Belgian Bone Club

Cavalier, Etienne
Kaufman, Jean-Marc
Nzeusseu Toukap, Adrien
Reginster, Jean-Yves
Rousseau, A.F.
Rozenberg, Serge
Scheen, André Jacques
Body, Jean-Jacques
Bergmann, Pierre
Bruyere, Olivier
Delanaye, Pierre
Durnez, A
Devogelaer, Jean-Pierre
Ferrari, Serge Livio Ivio S.L.
Gielen, Evelien
Goemaere, Stefan

Open link

Publication date

July 2016

DOI

10.1007/s00198-016-3561-3

Publisher

Springer Science and Business Media LLC

Abstract

The exact role of biochemical markers of bone turnover in the management of metabolic bone diseases remains a topic of controversy. In this consensus paper, the Belgian Bone Club aimed to provide a state of the art on the use of these biomarkers in different clinical or physiological situations like in postmenopausal women, osteoporosis in men, in elderly patients, in patients suffering from bone metastasis, in patients with chronic renal failure, in pregnant or lactating women, in intensive care patients, and in diabetics. We also gave our considerations on the analytical issues linked to the use of these biomarkers, on potential new emerging biomarkers, and on the use of bone turnover biomarkers in the follow-up of patients treated with n...