Contribution of a heparin-binding haemagglutinin interferon-gamma release assay to the detection of Mycobacterium tuberculosis infection in HIV-infected patients: comparison with the tuberculin skin test and the QuantiFERON-TB Gold In-tube.
- Wyndham-Thomas, Chloe
- Dirix, Violette
- Schepers, Kinda
- Martin, Charlotte
- Hildebrand, Marc
- Goffard, Jean-Christophe
- Domont, Fanny
- Libin, Myriam
- Loyens, Marc
- Locht, Camille
- Van Vooren, Jean-Paul
- Mascart, Françoise
Publication date
January 2015
DOI Publisher
Springer Science and Business Media LLC ISSN
1471-2334 Citation count (estimate)
7Abstract
The screening and treatment of latent tuberculosis (TB) infection reduces the risk of progression to active disease and is currently recommended for HIV-infected patients. The aim of this study is to evaluate, in a low TB incidence setting, the potential contribution of an interferon-gamma release assay in response to the mycobacterial latency antigen Heparin-Binding Haemagglutinin (HBHA-IGRA), to the detection of Mycobacterium tuberculosis infection in HIV-infected patients.SCOPUS: ar.jSCOPUS: ar.jinfo:eu-repo/semantics/publishe
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