Réparation du nerf périphérique :intérêt des colles biologiques et de la suture épipérineurale dans les interventions tardives. Etude expérimentale chez le rat

In order to approximate as close as possible genuine clinical conditions, the sciatic nerve of the rat was divided and then repaired after a delay of one or seven days either by application of a biological glue or by an epiperineural suture technique. The metabolic activity of the sciatic nerve Schwann cells - whether located in the distal or the proximal ends - and that of the (fast acting) white gastrocnemius and (slow acting) red soleus muscle were assessed using 32P-radiolabeled acid-soluble phosphates. Delayed repair, as judged by our biochemical criteria, was equivalent whatever method, biological glue or suture, was used. The frozen and lyophilized forms of the biological glue provided similar results. © 1985 Société d'Édition de l'Association d'Enseignement Médical des Hôpitaux de Paris.SCOPUS: ar.j