Traitement des cancers bronchiques non à petites cellules de petit stade. Recommandations de pratique clinique de I'European Cancer Working Party.

The present updated guidelines on the management of resectable non-small cell lung cancer (NSCLC) formulated by the ELCWP are designed to answer the following questions: 1) Is conventional surgery the best treatment for potentially resectable cancer? 2) What is the definition of a complete resection? 3) Should we make a systematic lymphadenectomy in case of surgery for a N0 or N1 tumor? 4) What is the role of radiation therapy after complete resection? 5) In case of clinical stage I or II, should administer adjuvant or neoadjuvant chemotherapy? 6) In case of pathological stage I or II, should administer adjuvant chemotherapy? 7) In case of complete resection for stage IIIA N2 disease, should be offered adjuvant therapy and if so which one: chemotherapy, radiotherapy, chemoradiotherapy? 8) In case of clinical stage IIIA or B, what are the indications for surgery after induction therapy? 9) In case of clinical stage IIIA or B, if surgical indication is retained, should we do an induction treatment, and if so, which one? 10) In case of incomplete resection after primary surgery, what should be the postoperative therapy? 11) In case of (neo)adjuvant chemotherapy, which association should be offered and what dosage of cisplatin to be prescribed? 12) Can stereotactic radiotherapy replace surgery in operable patients? 13) What is proposed for the patient unfit for conventional surgery treatment? 14) Have targeted therapies a place in the treatment ?English AbstractJournal Article