Endotoxine et asthme

Exposure to some airborne allergens plays a major etiopathogenic role in asthma. However, exposure to domestic airborne allergens appears to be only one of several factors leading to asthma, particularly in severe asthma. Endotoxins are pro-inflammatory substances produced by Gram negative bacteria, associated with several occupational chronic obstructuve pulmonary diseases. The possible role of exposure to endotoxin from house dust in domestic asthma is discussed in this review. © Expansion Scientifique Française, 1996.SCOPUS: ar.j